[HTML][HTML] The Many Faces of Enterococcus spp.—Commensal, Probiotic and Opportunistic Pathogen

B Krawczyk, P Wityk, M Gałęcka, M Michalik - Microorganisms, 2021‏ - mdpi.com
Enterococcus spp. are Gram-positive, facultative, anaerobic cocci, which are found in the
intestinal flora and, less frequently, in the vagina or mouth. Enterococcus faecalis and …

Dr. Jekyll and Mr. Hide: how Enterococcus faecalis subverts the host immune response to cause infection

PHN Kao, KA Kline - Journal of molecular biology, 2019‏ - Elsevier
Enterococcus faecalis, a ubiquitous member of the healthy human gut microbiota, is also a
common opportunistic pathogen and leading cause of nosocomial infections. This tenacious …

Enterococcal metabolite cues facilitate interspecies niche modulation and polymicrobial infection

D Keogh, WH Tay, YY Ho, JL Dale, S Chen… - Cell host & …, 2016‏ - cell.com
Enterococcus faecalis is frequently associated with polymicrobial infections of the urinary
tract, indwelling catheters, and surgical wound sites. E. faecalis co-exists with Escherichia …

Adaptation to adversity: the intermingling of stress tolerance and pathogenesis in enterococci

AO Gaca, JA Lemos - Microbiology and Molecular Biology …, 2019‏ - journals.asm.org
Enterococcus is a diverse and rugged genus colonizing the gastrointestinal tract of humans
and numerous hosts across the animal kingdom. Enterococci are also a leading cause of …

Bacterial chitinases and chitin-binding proteins as virulence factors

RF Frederiksen, DK Paspaliari, T Larsen… - …, 2013‏ - microbiologyresearch.org
Bacterial chitinases (EC 3.2. 1.14) and chitin-binding proteins (CBPs) play a fundamental
role in the degradation of the ubiquitous biopolymer chitin, and the degradation products …

Enterococcus faecalis antagonizes Pseudomonas aeruginosa growth in mixed-species interactions

CAZ Tan, LN Lam, G Biukovic, EYC Soh… - Journal of …, 2022‏ - journals.asm.org
Enterococcus faecalis is often coisolated with Pseudomonas aeruginosa in polymicrobial
biofilm-associated infections of wounds and the urinary tract. As a defense strategy, the host …

Extracellular electron transfer powers Enterococcus faecalis biofilm metabolism

D Keogh, LN Lam, LE Doyle, A Matysik, S Pavagadhi… - MBio, 2018‏ - journals.asm.org
Enterococci are important human commensals and significant opportunistic pathogens.
Biofilm-related enterococcal infections, such as endocarditis, urinary tract infections, wound …

Characterization of the chitinolytic machinery of Enterococcus faecalis V583 and high-resolution structure of its oxidative CBM33 enzyme

G Vaaje-Kolstad, LA Bøhle, S Gåseidnes… - Journal of molecular …, 2012‏ - Elsevier
Little information exists for the ability of enterococci to utilize chitin as a carbon source. We
show that Enterococcus faecalis V583 can grow on chitin, and we describe two proteins, a …

Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate

DE Sastre, N Sultana, M VAS Navarro… - Nature …, 2024‏ - nature.com
Bacteroidales (syn. Bacteroidetes) are prominent members of the human gastrointestinal
ecosystem mainly due to their efficient glycan-degrading machinery, organized into gene …

[HTML][HTML] Structural and electronic snapshots during the transition from a Cu (II) to Cu (I) metal center of a lytic polysaccharide monooxygenase by X-ray photoreduction

M Gudmundsson, S Kim, M Wu, T Ishida… - Journal of biological …, 2014‏ - Elsevier
Lytic polysaccharide monooxygenases (LPMOs) are a recently discovered class of enzymes
that employ a copper-mediated, oxidative mechanism to cleave glycosidic bonds. The LPMO …