Background The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Cardiovascular diseases (CVDs) have become the leading global cause of mortality,
prompting a heightened focus on identifying precise indicators for their assessment and …

Background: Emerging evidence suggests that elevated circulating levels of HDL-C (high-
density lipoprotein cholesterol) could be linked to an increased mortality risk. However, to …

Importance Body mass index (BMI; calculated as weight in kilograms divided by height in
meters squared) is a commonly used estimate of obesity, which is a complex trait affected by …

Importance Increased levels of high-density lipoprotein cholesterol (HDL-C) have been
associated with osteoporosis. Preclinical studies have reported that HDL-C reduces bone …

Abstract Purpose of Review Review updates for the association of HDL-cholesterol with
atherosclerotic cardiovascular disease (ASCVD) and discuss the approach to incorporating …

Background Recent studies have demonstrated that very high high-density lipoprotein
cholesterol (HDL-C) level was paradoxically linked with higher risk of cardiovascular …

Background Recent studies have reported associations between high plasma high-density
lipoprotein cholesterol (HDL-C) levels and risk of all-cause mortality, age-related macular …

Context Among children, evidence on long-term longitudinal associations of accelerometer-
measured sedentary time, light physical activity (LPA), and moderate to vigorous PA (MVPA) …

Abstract Background Clinical trials and Mendelian randomization (MR) studies reported null
effects of high-density lipoprotein cholesterol (HDL-C) on risk of cardiovascular disease …