Exclusion criteria and adverse events in perioperative trials of tranexamic acid: a systematic review and meta‐analysis

J Yates, I Perelman, S Khair, J Taylor, J Lampron… - …, 2019 - Wiley Online Library
BACKGROUND Tranexamic acid (TXA) is an inexpensive therapy effective at minimizing
perioperative blood loss and transfusion. However, it remains underutilized due to safety …

Drug treatment of chronic subdural hematoma

J Huang, C Gao, J Dong, J Zhang… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Chronic subdural hematoma (CSDH) is a common neurosurgical disease,
whose incidence has been steadily increasing with our aging population. While not …

Guidelines for the management of neonates and infants with hypoplastic left heart syndrome: the European Association for Cardio-Thoracic Surgery (EACTS) and the …

N Alphonso, A Angelini, DJ Barron… - European Journal of …, 2020 - academic.oup.com
Disclaimer 2020: The EACTS/AEPC Guidelines represent the views of the EACTS and the
AEPC and were produced after careful consideration of the scientific and medical …

Recent advances in the discovery and development of drugs targeting the kallikrein-kinin system

P Wisniewski, T Gangnus, BB Burckhardt - Journal of Translational …, 2024 - Springer
Background The kallikrein-kinin system is a key regulatory cascade involved in blood
pressure maintenance, hemostasis, inflammation and renal function. Currently, approved …

Antifibrinolytic drugs for the prevention of bleeding in pediatric cardiac surgery on cardiopulmonary bypass: a systematic review and meta-analysis

K Siemens, DP Sangaran, BJ Hunt… - Anesthesia & …, 2022 - journals.lww.com
BACKGROUND: Bleeding is one of the commonest complications affecting children
undergoing cardiac surgery on cardiopulmonary bypass. Antifibrinolytic drugs are part of a …

Use of antifibrinolytics in pediatric cardiac surgery: Where are we now?

D Faraoni, C Rahe, KA Cybulski - Pediatric Anesthesia, 2019 - Wiley Online Library
Fibrinolytic activation is a major and preventable source of bleeding in neonates and
children undergoing cardiac surgery with cardiopulmonary bypass. Based on the existing …

Efficacy and safety of aprotinin in paediatric cardiac surgery: a systematic review and meta-analysis

AG Atasever, M Eerens, R Van den Eynde… - European Journal of …, 2022 - journals.lww.com
BACKGROUND The relicensing of aprotinin in Europe and Canada has stimulated
discussions on its usefulness in paediatric cardiac surgery. OBJECTIVE To systematically …

Prophylactic use of antifibrinolytics during pediatric cardiac surgery with cardiopulmonary bypass on postoperative bleeding and transfusion: a systematic review and …

K Schertz, O Karam, M Demetres… - Pediatric Critical Care …, 2022 - journals.lww.com
Objectives: To determine the effect of intraoperative antifibrinolytics, including tranexamic
acid (TXA), aminocaproic acid (EACA), or aprotinin, on bleeding in children undergoing …

Paediatric trauma resuscitation: an update

TH Tosounidis, PV Giannoudis - European Journal of Trauma and …, 2016 - Springer
Purpose Paediatric trauma is the leading cause of mortality in children. Paediatric trauma
resuscitation is the first and foremost step towards a successful treatment and subsequent …

Массивная кровопотеря в педиатрической практике

КВ Пшениснов, ЮС Александрович - Гематология и …, 2020 - cyberleninka.ru
Введение. Массивная кровопотеря является одной из основных причин летальных
исходов и осложнений как у больных, нуждающихся в обширных хирургических …