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Metallic nanosystems in the development of antimicrobial strategies with high antimicrobial activity and high biocompatibility
K Skłodowski, SJ Chmielewska-Deptuła… - International journal of …, 2023 - mdpi.com
Antimicrobial resistance is a major and growing global problem and new approaches to
combat infections caused by antibiotic resistant bacterial strains are needed. In recent years …
combat infections caused by antibiotic resistant bacterial strains are needed. In recent years …
[HTML][HTML] Ceragenins and Ceragenin-Based Core-Shell Nanosystems as New Antibacterial Agents against Gram-Negative Rods Causing Nosocomial Infections
M Karasiński, U Wnorowska, B Durnaś, G Król… - Pathogens, 2023 - mdpi.com
The growing number of infections caused by multidrug-resistant bacterial strains, limited
treatment options, multi-species infections, high toxicity of the antibiotics used, and an …
treatment options, multi-species infections, high toxicity of the antibiotics used, and an …
[HTML][HTML] Bactericidal activity of ceragenin in combination with ceftazidime, levofloxacin, co-trimoxazole, and colistin against the opportunistic pathogen …
P Paprocka, A Mańkowska, K Skłodowski, G Król… - Pathogens, 2022 - mdpi.com
Background: Stenotrophomonas maltophilia (S. maltophilia) is an emerging opportunistic
Gram-negative rod causing nosocomial infections predominantly in immunocompromised …
Gram-negative rod causing nosocomial infections predominantly in immunocompromised …
Ceragenin CSA-13 displays high antibacterial efficiency in a mouse model of urinary tract infection
U Wnorowska, E Piktel, P Deptuła, T Wollny, G Król… - Scientific Reports, 2022 - nature.com
Ceragenins (CSAs) are synthetic, lipid-based molecules that display activities of natural
antimicrobial peptides. Previous studies demonstrated their high in vitro activity against …
antimicrobial peptides. Previous studies demonstrated their high in vitro activity against …
Searching for Conjugates as New Structures for Antifungal Therapies
I Muszalska-Kolos, PM Dwiecki - Journal of Medicinal Chemistry, 2024 - ACS Publications
The progressive increase in fungal infections and the decrease in the effectiveness of
current therapy explain research on new drugs. The synthesis of compounds with proven …
current therapy explain research on new drugs. The synthesis of compounds with proven …
Investigating the Effectiveness of Ceragenins against Acinetobacter baumannii to Develop New Antimicrobial and Anti-Adhesive Strategies
M Karasiński, U Wnorowska, T Daniluk… - International Journal of …, 2024 - mdpi.com
A growing body of experimental data indicates that ceragenins (CSAs), which mimic the
physicochemical properties of the host's cationic antimicrobial peptide, hold promise for the …
physicochemical properties of the host's cationic antimicrobial peptide, hold promise for the …
[HTML][HTML] Natural Antimicrobial Peptides and Their Synthetic Analogues for Effective Oral Microflora Control and Oral Infection Treatment—The Role of Ceragenins in …
M Czarnowski, U Wnorowska, M Łuckiewicz… - Pharmaceuticals, 2024 - mdpi.com
Oral diseases, both acute and chronic, of infectious or non-infectious etiology, represent
some of the most serious medical problems in dentistry. Data from the literature increasingly …
some of the most serious medical problems in dentistry. Data from the literature increasingly …
[HTML][HTML] Effect of Adding Gold Nanoparticles on the Anti-Candidal Activity and Release Profile of Itraconazole from Hydrogels
Featured Application The work presents information on the potential for the synthesis of
hydrogels comprising gold nanoparticles coated with itraconazole, together with an …
hydrogels comprising gold nanoparticles coated with itraconazole, together with an …