Recent progress in cartilage lubrication

W Lin, J Klein - Advanced Materials, 2021 - Wiley Online Library
Healthy articular cartilage, covering the ends of bones in major joints such as hips and
knees, presents the most efficiently‐lubricated surface known in nature, with friction …

Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022 - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Chondrocyte dedifferentiation and osteoarthritis (OA)

E Charlier, C Deroyer, F Ciregia, O Malaise… - Biochemical …, 2019 - Elsevier
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage
degradation but also synovial membrane inflammation, osteophyte formation and …

The role of chondrocyte hypertrophy and senescence in osteoarthritis initiation and progression

YA Rim, Y Nam, JH Ju - International journal of molecular sciences, 2020 - mdpi.com
Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the
adult population. OA is primarily caused by trauma induced by an external force or by age …

Synovitis in osteoarthritis: current understanding with therapeutic implications

A Mathiessen, PG Conaghan - Arthritis research & therapy, 2017 - Springer
Modern concepts of osteoarthritis (OA) have been forever changed by modern imaging
phenotypes demonstrating complex and multi-tissue pathologies involving cartilage …

Metabolic regulation of skeletal cell fate and function

S Stegen, G Carmeliet - Nature Reviews Endocrinology, 2024 - nature.com
Bone development and bone remodelling during adult life are highly anabolic processes
requiring an adequate supply of oxygen and nutrients. Bone-forming osteoblasts and bone …

Ageing and osteoarthritis

PK Sacitharan - Biochemistry and cell biology of ageing: part II clinical …, 2019 - Springer
The increase in global lifespan has in turn increased the prevalence of osteoarthritis which
is now the most common type of arthritis. Cartilage tissue located on articular joints erodes …

Aging and osteoarthritis: central role of the extracellular matrix

M Rahmati, G Nalesso, A Mobasheri… - Ageing research reviews, 2017 - Elsevier
Osteoarthritis (OA), is a major cause of severe joint pain, physical disability and quality of life
impairment in the aging population across the developed and develo** world. Increased …

The molecular interaction of collagen with cell receptors for biological function

J Elango, C Hou, B Bao, S Wang… - Polymers, 2022 - mdpi.com
Collagen, an extracellular protein, covers the entire human body and has several important
biological functions in normal physiology. Recently, collagen from non-human sources has …

Adhesive hydrogels in osteoarthritis: from design to application

WL Duan, LN Zhang, R Bohara… - Military Medical …, 2023 - Springer
Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7%
of the global population and more than 500 million people worldwide. One research frontier …