Cell–extracellular matrix mechanotransduction in 3D

A Saraswathibhatla, D Indana… - Nature Reviews Molecular …, 2023 - nature.com
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Breakthrough treatments for accelerated wound healing

BR Freedman, C Hwang, S Talbot, B Hibler… - Science …, 2023 - science.org
Skin injuries across the body continue to disrupt everyday life for millions of patients and
result in prolonged hospital stays, infection, and death. Advances in wound healing devices …

Floatable photocatalytic hydrogel nanocomposites for large-scale solar hydrogen production

WH Lee, CW Lee, GD Cha, BH Lee, JH Jeong… - Nature …, 2023 - nature.com
Storing solar energy in chemical bonds aided by heterogeneous photocatalysis is desirable
for sustainable energy conversion. Despite recent progress in designing highly active …

Supramolecular adhesive hydrogels for tissue engineering applications

Y Zhao, S Song, X Ren, J Zhang, Q Lin… - Chemical …, 2022 - ACS Publications
Tissue engineering is a promising and revolutionary strategy to treat patients who suffer the
loss or failure of an organ or tissue, with the aim to restore the dysfunctional tissues and …

Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

Effects of extracellular matrix viscoelasticity on cellular behaviour

O Chaudhuri, J Cooper-White, PA Janmey, DJ Mooney… - Nature, 2020 - nature.com
Substantial research over the past two decades has established that extracellular matrix
(ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading …

Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

Design, printing, and engineering of regenerative biomaterials for personalized bone healthcare

Z Jia, X Xu, D Zhu, Y Zheng - Progress in Materials Science, 2023 - Elsevier
Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

Current status and prospects of metal–organic frameworks for bone therapy and bone repair

M Li, S Yin, M Lin, X Chen, Y Pan, Y Peng… - Journal of Materials …, 2022 - pubs.rsc.org
With the development of society, traumatic bone defects caused by accidents, diseases and
surgeries have become common, eventually resulting in an increase in bone defects. The …

Engineered biomaterials for in situ tissue regeneration

AK Gaharwar, I Singh, A Khademhosseini - Nature Reviews Materials, 2020 - nature.com
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …