Oncolytic viruses are one of the most promising novel therapeutics for malignant cancers.
They selectively infect and kill cancer cells while sparing the normal counterparts, expose …

Current standard treatments of cancer can prolong survival of many cancer patients but
usually do not effectively cure the disease. Oncolytic virotherapy is an emerging therapeutic …

Hematological cancers such as leukemia, lymphoma, and multiple myeloma have
traditionally been treated with chemo and radiotherapy approaches. Introduction of …

Introduction: Over the last decade, advances in biological therapies have resulted in
remarkable clinical responses for the treatment of some previously incurable cancers …

Many common neoplasms are still noncurative with current standards of cancer therapy.
More therapeutic modalities need to be developed to significantly prolong the lives of …

Multiple myeloma is a complex disease and immune dysfunction has been known to play an
important role in the disease pathogenesis, progression, and drug resistance. Recent efforts …

Most patients with multiple myeloma (MM) undergoing autologous hematopoietic stem cell
transplantation (autoHCT) eventually relapse, perhaps due to the presence of clonal plasma …

The incidence of hematological malignancies such as multiple myeloma, leukemia, and
lymphoma has increased over time. Although bone marrow transplantation, immunotherapy …

Myxoma virus, a rabbit poxvirus, can efficiently infect various types of mouse and human
cancer cells. It is a strict rabbit-specific pathogen, and is thought to be safe as a therapeutic …

Pre-clinical in vivo models of multiple myeloma are essential tools for investigating the
pathophysiology of multiple myeloma and for testing new therapeutic agents and strategies …