Pulmonary drug delivery is a highly attractive topic for the treatment of infectious lung
diseases. Drug delivery via the pulmonary route offers unique advantages of no first-pass …

Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

Recent studies have unveiled the presence of nano-and microplastics (NMPs) within both
human and avian respiratory systems, prompting an exploration into the interactions …

Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

Assessing the toxicity of airborne particulate matter or the efficacy of inhaled drug depends
upon accurate estimates of deposited fraction of inhaled materials. In silico approaches can …

In silico methods can be used to estimate regional deposition of inhaled aerosols in regions
of the lung that are inaccessible by direct measurements. Knowledge of deposited dose is …

The outbreak of the coronavirus disease has drawn public attention to the transmission of
infectious pathogens, and as major carriers of those pathogens, respiratory droplets play an …

Most existing whole lung models neglect the airway deformation kinematics and assume the
lung airways are static. However, neglecting the airway deformation effect on pulmonary air …

Inhalation is a critical route through which substances can exert adverse effects in humans;
therefore, it is important to characterize the potential effects that inhaled substances may …

Dynamic modeling of how particulate matter (PM) transport, deposit, and translocate from
human respiratory systems to systemic regions subject to indoor and outdoor exposures are …