At specific stages of development, nerve and muscle cells generate spontaneous electrical
activity that is required for normal maturation of intrinsic excitability and synaptic connectivity …

In this review, we summarize the main stages of structural and functional development of
retinal ganglion cells (RGCs). We first consider the various mechanisms that are involved in …

Many factors have been shown to promote myelination, but few have been shown to be
inhibitory. Here, we show that polysialylated-neural cell adhesion molecule (PSA-NCAM) …

Neuronal discharge is driven by either synaptic input or cell-autonomous intrinsic
pacemaker activity. It is commonly assumed that the resting spike activity of retinal ganglion …

Birth is associated with a neuroprotective, oxytocin-mediated abrupt excitatory-to-inhibitory
GABA shift that is abolished in autism, and its restoration attenuates the disorder in offspring …

Retinal ganglion cells (RGCs) are the output neurons of the retina, sending their signals via
the optic nerve to many different targets in the thalamus and brainstem. These cells are …

Myelinated fibres are characterized by the aggregation of Nav1. 6 sodium channels within
the axon membrane at nodes of Ranvier, where their presence supports saltatory …

In this review, we summarize studies investigating the types and distribution of voltage-and
calcium-gated ion channels in the different classes of retinal neurons: rods, cones …

Voltage-and current-clamp recordings were made from acute slices of mouse cerebral
cortex from embryonic day 14 to postnatal day 17. We targeted cells in the migratory …

Information in a spike train is limited by variability in the spike timing. This variability is
caused by noise from several sources including synapses and membrane channels; but …