Mathematical modeling has played a prominent and necessary role in the current
coronavirus disease 2019 (COVID-19) pandemic, with an increasing number of models …

The continued growth of the world's population and increased interconnectivity heighten the
risk that infectious diseases pose for human health worldwide. Epidemiological modelling is …

Community-based strategies to strengthen men’s engagement in the HIV care cascade in
sub-Saharan Africa | PLOS Medicine Skip to main content Advertisement PLOS Medicine Browse …

Background Substantial reductions in adult mortality have been observed in South Africa
since the mid-2000s, but there has been no formal evaluation of how much of this decline is …

The efficacy of antiretroviral therapy is significantly compromised by medication non-
adherence. Long-acting enteral systems that can ease the burden of daily adherence have …

Individual-based models provide modularity and structural flexibility necessary for modeling
of infectious diseases at the within-host and population levels, but are challenging to …

Daily oral tenofovir disoproxil fumarate and emtricitabine (TDF/FTC) as HIV pre-exposure
prophylaxis (PrEP) is a safe and effective method for HIV prevention and offers potential to …

Background: Four of the largest HIV prevention trials have been conducted in sub-Saharan
Africa, enrolling hundreds of thousands of participants in catchment areas of millions of …

Background Including structural determinants (eg criminalisation, stigma, inequitable gender
norms) in dynamic HIV transmission models is important to help quantify their population …

Background Different models of sexually transmitted infections (STIs) can yield substantially
different conclusions about STI epidemiology, and it is important to understand how and why …