Reading, writing and erasing mRNA methylation
RNA methylation to form N 6-methyladenosine (m6A) in mRNA accounts for the most
abundant mRNA internal modification and has emerged as a widespread regulatory …
abundant mRNA internal modification and has emerged as a widespread regulatory …
Where, when, and how: context-dependent functions of RNA methylation writers, readers, and erasers
Cellular RNAs are naturally decorated with a variety of chemical modifications. The
structural diversity of the modified nucleosides provides regulatory potential to sort groups of …
structural diversity of the modified nucleosides provides regulatory potential to sort groups of …
The architecture of SARS-CoV-2 transcriptome
D Kim, JY Lee, JS Yang, JW Kim, VN Kim, H Chang - Cell, 2020 - cell.com
SARS-CoV-2 is a betacoronavirus responsible for the COVID-19 pandemic. Although the
SARS-CoV-2 genome was reported recently, its transcriptomic architecture is unknown …
SARS-CoV-2 genome was reported recently, its transcriptomic architecture is unknown …
Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms
X **, JS Lian, JH Hu, J Gao, L Zheng, YM Zhang… - Gut, 2020 - gut.bmj.com
Objective The SARS-CoV-2-infected disease (COVID-19) outbreak is a major threat to
human beings. Previous studies mainly focused on Wuhan and typical symptoms. We …
human beings. Previous studies mainly focused on Wuhan and typical symptoms. We …
The role of m6A RNA methylation in human cancer
XY Chen, J Zhang, JS Zhu - Molecular cancer, 2019 - Springer
Abstract N 6-methyladenosine (m 6 A) is identified as the most common, abundant and
conserved internal transcriptional modification, especially within eukaryotic messenger …
conserved internal transcriptional modification, especially within eukaryotic messenger …
The RNA modification N6-methyladenosine as a novel regulator of the immune system
Protection from harmful pathogens depends on activation of the immune system, which
relies on tight regulation of gene expression. Recently, the RNA modification N 6 …
relies on tight regulation of gene expression. Recently, the RNA modification N 6 …
Gene2vec: gene subsequence embedding for prediction of mammalian N6-methyladenosine sites from mRNA
N 6-Methyladenosine (m6A) refers to methylation modification of the adenosine nucleotide
acid at the nitrogen-6 position. Many conventional computational methods for identifying N 6 …
acid at the nitrogen-6 position. Many conventional computational methods for identifying N 6 …
[HTML][HTML] METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection
N Li, H Hui, B Bray, GM Gonzalez, M Zeller… - Cell reports, 2021 - cell.com
It is urgent and important to understand the relationship of the widespread severe acute
respiratory syndrome coronavirus clade 2 (SARS-CoV-2) with host immune response and …
respiratory syndrome coronavirus clade 2 (SARS-CoV-2) with host immune response and …
m6A modification controls the innate immune response to infection by targeting type I interferons
Abstract N6-methyladenosine (m6A) is the most common mRNA modification. Recent
studies have revealed that depletion of m6A machinery leads to alterations in the …
studies have revealed that depletion of m6A machinery leads to alterations in the …
Rethinking m6A Readers, Writers, and Erasers
In recent years, m6A has emerged as an abundant and dynamically regulated modification
throughout the transcriptome. Recent technological advances have enabled the …
throughout the transcriptome. Recent technological advances have enabled the …