Abstract Withania somnifera (L.) Dunal (Solanaceae) has been used as a traditional
Rasayana herb for a long time. Traditional uses of this plant indicate its ameliorative …

Neurodegenerative diseases are characterised by progressive damage to the nervous
system including the selective loss of vulnerable populations of neurons leading to motor …

Although women experience significantly higher tau burden and increased risk for
Alzheimer's disease (AD) than men, the underlying mechanism for this vulnerability has not …

Accumulation of misfolded protein aggregates is a hallmark event in many age-related
protein misfolding disorders, including some of the most prevalent and insidious …

Besides motor symptoms, many individuals with Parkinson's disease develop cognitive
impairment perhaps due to coexisting α-synuclein and Alzheimer's disease pathologies and …

Circular RNA s (circ RNA s) are brain‐abundant RNA s of mostly unknown functions. To
seek their roles in Parkinson's disease (PD), we generated an RNA sequencing resource of …

Since the initial description of apoptosis, a number of different forms of cell death have been
described. In this review we will focus on classic caspase-dependent apoptosis and its …

Laser capture microscopy (LCM) coupled with global transcriptome profiling could enable
precise analyses of cell populations without the need for tissue dissociation, but has so far …

In a range of neurological conditions, including movement disorders, sex-related differences
are emerging not only in brain anatomy and function, but also in pathogenesis, clinical …

The role of brain cholesterol metabolism in Alzheimer's disease (AD) remains unclear.
Peripheral and brain cholesterol levels are largely independent due to the impermeability of …