Ultra-high-performance liquid chromatography high-resolution mass spectrometry (UHPLC–
HRMS) variants currently represent the best tools to tackle the challenges of complexity and …

The identification of actionable tumor antigens is indispensable for the development of
several cancer immunotherapies, including T cell receptor–transduced T cells and patient …

Emerging evidence points toward an intricate relationship between the pandemic of
coronavirus disease 2019 (COVID-19) and diabetes. While preexisting diabetes is …

Data-independent acquisition modes isolate and concurrently fragment populations of
different precursors by cycling through segments of a predefined precursor m/z range …

Despite the established dogma of central nervous system (CNS) immune privilege,
neuroimmune interactions play an active role in diverse neurological disorders. However …

Single‐cell technologies are revolutionizing biology but are today mainly limited to imaging
and deep sequencing. However, proteins are the main drivers of cellular function and in …

Mass spectrometry (MS)-based proteomics aims to characterize comprehensive proteomes
in a fast and reproducible manner. Here we present the narrow-window data-independent …

Elucidating the wiring diagram of the human cell is a central goal of the postgenomic era.
We combined genome engineering, confocal live-cell imaging, mass spectrometry, and data …

Molecular networking has become a key method to visualize and annotate the chemical
space in non-targeted mass spectrometry data. We present feature-based molecular …

MaxDIA is a software platform for analyzing data-independent acquisition (DIA) proteomics
data within the MaxQuant software environment. Using spectral libraries, MaxDIA achieves …