From microbiome composition to functional engineering, one step at a time
Communities of microorganisms (microbiota) are present in all habitats on Earth and are
relevant for agriculture, health, and climate. Deciphering the mechanisms that determine …
relevant for agriculture, health, and climate. Deciphering the mechanisms that determine …
<? mode longmeta?> SPIRE: a Searchable, Planetary-scale mIcrobiome REsource
Meta'omic data on microbial diversity and function accrue exponentially in public
repositories, but derived information is often siloed according to data type, study or sampled …
repositories, but derived information is often siloed according to data type, study or sampled …
Rapid species-level metagenome profiling and containment estimation with sylph
Profiling metagenomes against databases allows for the detection and quantification of
microorganisms, even at low abundances where assembly is not possible. We introduce …
microorganisms, even at low abundances where assembly is not possible. We introduce …
Removal of false positives in metagenomics-based taxonomy profiling via targeting Type IIB restriction sites
Accurate species identification and abundance estimation are critical for the interpretation of
whole metagenome sequencing (WMS) data. Yet, existing metagenomic profilers suffer from …
whole metagenome sequencing (WMS) data. Yet, existing metagenomic profilers suffer from …
[HTML][HTML] A cryptic plasmid is among the most numerous genetic elements in the human gut
EC Fogarty, MS Schechter, K Lolans, ML Sheahan… - Cell, 2024 - cell.com
Plasmids are extrachromosomal genetic elements that often encode fitness-enhancing
features. However, many bacteria carry" cryptic" plasmids that do not confer clear beneficial …
features. However, many bacteria carry" cryptic" plasmids that do not confer clear beneficial …
Multi-biome analysis identifies distinct gut microbial signatures and their crosstalk in ulcerative colitis and Crohn's disease
S Akiyama, S Nishijima, Y Kojima, M Kimura… - Nature …, 2024 - nature.com
The integrative multi-kingdom interaction of the gut microbiome in ulcerative colitis (UC) and
Crohn's disease (CD) remains underinvestigated. Here, we perform shotgun metagenomic …
Crohn's disease (CD) remains underinvestigated. Here, we perform shotgun metagenomic …
The mOTUs online database provides web-accessible genomic context to taxonomic profiling of microbial communities
Determining the taxonomic composition (taxonomic profiling) is a fundamental task in
studying environmental and host-associated microbial communities. However, genome …
studying environmental and host-associated microbial communities. However, genome …
The NEREA Augmented Observatory: an integrative approach to marine coastal ecology
Abstract The NEREA (Naples Ecological REsearch for Augmented observatories) initiative
aims to establish an augmented observatory in the Gulf of Naples (GoN), designed to …
aims to establish an augmented observatory in the Gulf of Naples (GoN), designed to …
KMCP: accurate metagenomic profiling of both prokaryotic and viral populations by pseudo-map**
W Shen, H **ang, T Huang, H Tang, M Peng… - …, 2023 - academic.oup.com
Motivation The growing number of microbial reference genomes enables the improvement
of metagenomic profiling accuracy but also imposes greater requirements on the indexing …
of metagenomic profiling accuracy but also imposes greater requirements on the indexing …
Narrow host range phages infect essential bacteria for water purification reactions in groundwater-fed rapid sand filters
Biofiltration is used worldwide to provide safe potable water due to its low energy demand
and excellent treatment performance. For instance, in Denmark, over 95% of drinking water …
and excellent treatment performance. For instance, in Denmark, over 95% of drinking water …