Fluorescence lifetime imaging (FLIM) is a key fluorescence microscopy technique to map the
environment and interaction of fluorescent probes. It can report on photophysical events that …

The field of biomedical optics has matured rapidly over the last decade and is poised to
make a significant impact on patient care. In particular, wide-field (typically> 5 cm), planar …

In this paper, we report on SwissSPAD2, an image sensor with 512× 512 photon-counting
pixels, each comprising a single-photon avalanche diode (SPAD), a 1-b memory, and a …

Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique offering profound
insights into a broad spectrum of biological processes such as metabolic imaging, protein …

Fluorescence lifetime imaging microscopy (FLIM) has been rapidly developed over the past
30 years and widely applied in biomedical engineering. Recent progress in fluorophore …

Amyloid peptide (Aβ) is generated by sequential cleavage of the amyloid precursor protein
(APP) by β‐secretase (Bacel) and γ‐secretase. Aβ production increases after plasma …

In the last decade or so, it has been realised that membranes do not just have a lipid-bilayer
structure in which proteins are embedded or with which they associate. Structures are …

Background Fluorescence lifetime imaging (FLIM) is a novel imaging technique that
generates image contrast between different states of tissue due to differences in …

We demonstrate diffraction limited multiphoton imaging in a massively parallel, fully
addressable time-resolved multi-beam multiphoton microscope capable of producing …

We describe a novel method for quantitatively map** fluidic temperature with high spatial
resolution within microchannels using fluorescence lifetime imaging in an optically …