[HTML][HTML] Combining brain perturbation and neuroimaging in non-human primates
Brain perturbation studies allow detailed causal inferences of behavioral and neural
processes. Because the combination of brain perturbation methods and neural …
processes. Because the combination of brain perturbation methods and neural …
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys
Y Nagai, N Miyakawa, H Takuwa, Y Hori… - Nature …, 2020 - nature.com
The chemogenetic technology designer receptors exclusively activated by designer drugs
(DREADDs) afford remotely reversible control of cellular signaling, neuronal activity and …
(DREADDs) afford remotely reversible control of cellular signaling, neuronal activity and …
Applications of chemogenetics in non-human primates
Due to its low invasiveness and controllability, chemogenetic approaches offer a highly
attractive option to modulate neuronal activity in basic research and future clinical …
attractive option to modulate neuronal activity in basic research and future clinical …
High-potency ligands for DREADD imaging and activation in rodents and monkeys
Abstract Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a
popular chemogenetic technology for manipulation of neuronal activity in uninstrumented …
popular chemogenetic technology for manipulation of neuronal activity in uninstrumented …
Chemogenetic attenuation of cortical seizures in nonhuman primates
Epilepsy is a disorder in which abnormal neuronal hyperexcitation causes several types of
seizures. Because pharmacological and surgical treatments occasionally interfere with …
seizures. Because pharmacological and surgical treatments occasionally interfere with …
Macaques exhibit implicit gaze bias anticipating others' false-belief-driven actions via medial prefrontal cortex
T Hayashi, R Akikawa, K Kawasaki, J Egawa… - Cell Reports, 2020 - cell.com
The ability to infer others' mental states is essential to social interactions. This ability,
critically evaluated by testing whether one attributes false beliefs (FBs) to others, has been …
critically evaluated by testing whether one attributes false beliefs (FBs) to others, has been …
Multiscale chemogenetic dissection of fronto-temporal top-down regulation for object memory in primates
Visual object memory is a fundamental element of various cognitive abilities, and the
underlying neural mechanisms have been extensively examined especially in the anterior …
underlying neural mechanisms have been extensively examined especially in the anterior …
Post-error recruitment of frontal sensory cortical projections promotes attention in mice
KJ Norman, JS Riceberg, H Koike, J Bateh… - Neuron, 2021 - cell.com
The frontal cortex, especially the anterior cingulate cortex area (ACA), is essential for
exerting cognitive control after errors, but the mechanisms that enable modulation of …
exerting cognitive control after errors, but the mechanisms that enable modulation of …
Chemogenetic manipulations of ventral tegmental area dopamine neurons reveal multifaceted roles in cocaine abuse
Ventral tegmental area (VTA) dopamine (DA) neurons perform diverse functions in
motivation and cognition, but their precise roles in addiction-related behaviors are still …
motivation and cognition, but their precise roles in addiction-related behaviors are still …
Primate preoptic neurons drive hypothermia and cold defense
Maintaining body temperature within a narrow range is vital for warm-blooded animals. In
rodents, the preoptic area (POA) of the hypothalamus detects and regulates core body …
rodents, the preoptic area (POA) of the hypothalamus detects and regulates core body …