The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Optical imaging has been essential for scientific observations to date, however its
biomedical applications has been restricted due to its poor penetration through tissues. In …

T cells are an essential part of the immune system with crucial roles in adaptive response
and the maintenance of tissue homeostasis. Depending on their microenvironment, T cells …

Real‐time optical imaging of immune cells can contribute to understanding their
pathophysiological roles, which still remains challenging. Current sensitive …

Interest in self-immolative chemistry has grown over the past decade with more research
groups harnessing the versatility to control the release of a compound from a larger …

Chemotherapy‐induced peripheral neuropathy (CIPN) has a high prevalence but is poorly
managed for cancer patients due to the lack of reliable and sensitive diagnostic techniques …

Real‐time imaging of immune systems benefits early diagnosis of disease and precision
immunotherapy; however, most existing imaging probes either have “always‐on” signals …

Cytotoxic T lymphocytes (CTLs) are important immune cells, and their activation is a key step
for cancer immunotherapy. Precise evaluation of CTL activity in vivo provides a powerful tool …

Proteases are excellent biomarkers for a variety of diseases, offer multiple opportunities for
diagnostic applications and are valuable targets for therapy. From a chemistry-based …

Triggered chemiluminescence emission of spiroadamantane-1, 2-dioxetanes to detect
bioanalytes has fueled the emerging popularity of chemiluminescence imaging in live …