The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …

While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …

Light, oxygen and photosensitizers (PSs) are the three separate elements that have been
applied in combination in the phototherapy of cancers in the past decades. Currently …

Cancer is an aggressive disease involving abnormal cell growth with the potential to invade
other parts of the body. Despite intense interest from clinicians and biomedical researchers …

Current platinum-based drugs used in chemotherapy, like cisplatin and its derivatives, are
greatly limited due to side-effects and drug resistance. This has inspired the search for novel …

Platinum-based anticancer drugs represented by cisplatin play important roles in the
treatment of various solid tumors. However, their applications are largely compromised by …

In recent years, targeted therapies have raised increasing interest as effective strategies to
improve therapeutic efficiency, reduce the impact of adverse side effects, and overcome …

Pincer complexes featuring tunable tridentate ligand frameworks are one of the most actively
studied classes of metal-based complexes. Currently, growing attention is devoted to the …

In the framework of our attempts to develop cyclometalated Pt (II) complexes toward
bifunctional targeting inhibitors or agents for photodynamic therapy, diagnostics, and …

Photodynamic therapy is a light-activated medical technique, which has received increasing
attention within the last decade to treat various diseases including bacterial, viral or fungal …