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Enzyme modulators and treatments
DL Flynn, PA Petillo - US Patent 8,163,756, 2012 - Google Patents
0* S ([8*])(= O)= NC. CCCCCC [4*] C (O) C (C) C.[4*] N ([4*]) C (= C) C.[4*] N ([4*]) C (= C)
C.[5*] C (= C) C.[5*] C (= C) C.[5*] C (= C) CC.[5*] C (= O) OCC.[5*] CC.[5*] CC (= O) …
C.[5*] C (= C) C.[5*] C (= C) C.[5*] C (= C) CC.[5*] C (= O) OCC.[5*] CC.[5*] CC (= O) …
Anti-inflammatory medicaments
DL Flynn, PA Petillo - US Patent 7,144,911, 2006 - Google Patents
Novel compounds and methods of using those compounds for the treatment of inflammatory
conditions are provided. In a preferred embodiment, modulation of the activation state of p38 …
conditions are provided. In a preferred embodiment, modulation of the activation state of p38 …
Combination therapy for the treatment of mastocytosis
DL Flynn, BD Smith, A Gupta - US Patent 12,102,620, 2024 - Google Patents
CEFJVGZHQAGLHS-UHFFFAOYSA-N ripretinib Chemical compound O= C1N (CC) C2= CC
(NC)= NC= C2C= C1C (C (= CC= 1F) Br)= CC= 1NC (= O) NC1= CC= CC= C1 …
(NC)= NC= C2C= C1C (C (= CC= 1F) Br)= CC= 1NC (= O) NC1= CC= CC= C1 …
Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
DL Flynn, PA Petillo, MD Kaufman - US Patent 7,790,756, 2010 - Google Patents
The present invention is concerned with novel compounds useful in the treatment of
hyperproliferative diseases and mammalian cancers, especially human cancers. The inven …
hyperproliferative diseases and mammalian cancers, especially human cancers. The inven …
Substituted 3-carboxamido isoxazoles as kinase modulators
SA Mehta, RM Grotzfeld, ZV Milanov, AG Lai… - US Patent …, 2010 - Google Patents
A6 IK3I/506 30 6 8: The invention provides methods and compositions for treat A6
IK3I/52(2006.015 ing conditions mediated by various kinases wherein Substi A6 …
IK3I/52(2006.015 ing conditions mediated by various kinases wherein Substi A6 …
Amide derivatives as ABL modulators
R Grotzfeld, H Patel, S Mehta, Z Milanov… - US Patent App. 10 …, 2005 - Google Patents
The invention provides methods and compositions for treat ing conditions mediated by abl
wherein derivatives of amide compounds are employed. The invention also provides …
wherein derivatives of amide compounds are employed. The invention also provides …
Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
DL Flynn, PA Petillo, MD Kaufman, WC Patt - US Patent 8,188,113, 2012 - Google Patents
2007-12-10 Assigned to DECIPHERA PHARMACEUTICALS, LLC reassignment
DECIPHERA PHARMACEUTICALS, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
DECIPHERA PHARMACEUTICALS, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
Amide derivatives as FLT-3 modulators
S Mehta, R Grotzfeld, Z Milanov, A Lai… - US Patent App. 10 …, 2005 - Google Patents
The invention provides methods and compositions for treat ing conditions mediated by filt-3
wherein derivatives of amide compounds are employed. The invention also pro vides …
wherein derivatives of amide compounds are employed. The invention also pro vides …
Combinations containing a 4-acylaminopyridine derivative
C Barlow, TA Carter, A Morse, K Treuner… - US Patent …, 2011 - Google Patents
3,941,785 A 3, 1976 Clarke et al. 3,960,927 A 6, 1976 Metcalfetal. 4,007,196 A 2f1977
Christensen et al. 4,024, 175 A 5/1977 Satzinger et al. 4,036,840 A 7, 1977 O'Brien et al …
Christensen et al. 4,024, 175 A 5/1977 Satzinger et al. 4,036,840 A 7, 1977 O'Brien et al …
Anti-inflammatory medicaments
DL Flynn, PA Petillo - US Patent 7,666,895, 2010 - Google Patents
5,103,014 A 4, 1992 Musser et al. 5,494,925 A 2f1996 Court et al. 6,020,357 A 2/2000 Pinto
et al. 6,235,786 B1 5, 2001 Dai et al. 6,294,573 B1 9, 2001 Curtin et al. 6,319,921 B1 1 …
et al. 6,235,786 B1 5, 2001 Dai et al. 6,294,573 B1 9, 2001 Curtin et al. 6,319,921 B1 1 …