Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset
dementia and presents with early social–emotional–behavioural and/or language changes …

The most definitive classification systems for dementia are based on the underlying
pathology which, in turn, is categorized largely according to the observed accumulation of …

PURPOSE OF REVIEW Early-onset Alzheimer disease (AD) is defined as having an age of
onset younger than 65 years. While early-onset AD is often overshadowed by the more …

Progressive supranuclear palsy (PSP), previously believed to be a common cause of
atypical parkinsonism, is now recognised as a range of motor and behavioural syndromes …

The primary progressive aphasias are a heterogeneous group of focal 'language-
led'dementias that pose substantial challenges for diagnosis and management. Here we …

Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly with a progressive decline in cognitive function significantly affecting quality of life …

Importance Neuronal and axonal destruction are hallmarks of neurodegenerative diseases,
but it is difficult to estimate the extent and progress of the damage in the disease process …

Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …

Objective To estimate the prevalence of amyloid positivity, defined by positron emission
tomography (PET)/cerebrospinal fluid (CSF) biomarkers and/or neuropathological …

The syndromes caused by frontotemporal lobar degeneration have highly heterogeneous
and overlap** clinical features. There has been great progress in the refinement of clinical …