Using machine learning to individualize treatment effect estimation: Challenges and opportunities

A Curth, RW Peck, E McKinney… - Clinical …, 2024 - Wiley Online Library
The use of data from randomized clinical trials to justify treatment decisions for real‐world
patients is the current state of the art. It relies on the assumption that average treatment …

Causal transformer for estimating counterfactual outcomes

V Melnychuk, D Frauen… - … conference on machine …, 2022 - proceedings.mlr.press
Estimating counterfactual outcomes over time from observational data is relevant for many
applications (eg, personalized medicine). Yet, state-of-the-art methods build upon simple …

Generating synthetic mixed-type longitudinal electronic health records for artificial intelligent applications

J Li, BJ Cairns, J Li, T Zhu - NPJ digital medicine, 2023 - nature.com
The recent availability of electronic health records (EHRs) have provided enormous
opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has …

Cardiovascular care with digital twin technology in the era of generative artificial intelligence

PM Thangaraj, SH Benson, EK Oikonomou… - European Heart …, 2024 - academic.oup.com
Digital twins, which are in silico replications of an individual and its environment, have
advanced clinical decision-making and prognostication in cardiovascular medicine. The …

Warpformer: A multi-scale modeling approach for irregular clinical time series

J Zhang, S Zheng, W Cao, J Bian, J Li - Proceedings of the 29th ACM …, 2023 - dl.acm.org
Irregularly sampled multivariate time series are ubiquitous in various fields, particularly in
healthcare, and exhibit two key characteristics: intra-series irregularity and inter-series …

Accounting for informative sampling when learning to forecast treatment outcomes over time

T Vanderschueren, A Curth… - International …, 2023 - proceedings.mlr.press
Abstract Machine learning (ML) holds great potential for accurately forecasting treatment
outcomes over time, which could ultimately enable the adoption of more individualized …

Transfer learning on heterogeneous feature spaces for treatment effects estimation

I Bica, M van der Schaar - Advances in Neural Information …, 2022 - proceedings.neurips.cc
Consider the problem of improving the estimation of conditional average treatment effects
(CATE) for a target domain of interest by leveraging related information from a source …

Estimating average causal effects from patient trajectories

D Frauen, T Hatt, V Melnychuk… - Proceedings of the AAAI …, 2023 - ojs.aaai.org
In medical practice, treatments are selected based on the expected causal effects on patient
outcomes. Here, the gold standard for estimating causal effects are randomized controlled …

Reliable off-policy learning for dosage combinations

J Schweisthal, D Frauen… - Advances in Neural …, 2023 - proceedings.neurips.cc
Decision-making in personalized medicine such as cancer therapy or critical care must often
make choices for dosage combinations, ie, multiple continuous treatments. Existing work for …

A deep learning approach for fairness-based time of use tariff design

Y Han, JCK Lam, VOK Li, D Newbery, P Guo, K Chan - Energy Policy, 2024 - Elsevier
Time of use (TOU) tariffs aim to shape demand by reducing peak demand. This is significant
given the increasing pressure on peak energy supply, particularly in Europe, where peak …