Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

Evidence is increasing that disturbances in the gut microbiome may play a significant role in
the etiology of obesity and type 2 diabetes. The short chain fatty acid butyrate, a major end …

The intestinal epithelial barrier, composed of epithelial cells, tight junction proteins and
intestinal secretions, prevents passage of luminal substances and antigens through the …

AIM To investigate whether gut microbiota metabolite sodium butyrate (NaB) is an effective
substance for attenuating non-alcoholic fatty liver disease (NAFLD) and the internal …

Cardiovascular diseases (CVD) are major causes of death worldwide. Recently, new roles
for intestinal microbiota in pathology and treatment of CVD have been proposed. Butyrate, a …

Increasing experimental and clinical evidence points toward a very important role for the gut
microbiome and its associated metabolism in human health and disease, including in …

G-protein-coupled receptors are a diverse class of cell surface receptors that orchestrate
numerous physiological functions. The G-protein-coupled receptors, GPR41 and GPR43 …

Metabolic syndrome (MetS) and the associated incidence of cardiovascular disease and
type 2 diabetes represents a significant contributor to morbidity and mortality worldwide …

Dyslipidemia is a multifaceted condition with various genetic and environmental factors
contributing to its pathogenesis. Further, this condition represents an important risk factor for …

The role of the gut microbiome in human health is becoming apparent. The major functional
impact of the gut microbiome is transmitted through the microbial metabolites that are …