The anti-inflammatory role of SSRI and SNRI in the treatment of depression: a review of human and rodent research studies

V Dionisie, GA Filip, MC Manea, M Manea… - Inflammopharmacology, 2021 - Springer
Rationale Depression has the topmost prevalence of all psychiatric diseases. It is
characterized by a high recurrence rate, disability, and numerous and mostly unclear …

Antidepressants' effects on testosterone and estrogens: What do we know?

P Pavlidi, N Kokras, C Dalla - European journal of pharmacology, 2021 - Elsevier
Various antidepressants are commonly used to treat depression and anxiety disorders, and
sex differences have been identified in their efficacy and side effects. Steroids, such as …

PI3K–AKT signaling activation and icariin: The potential effects on the perimenopausal depression-like rat model

LH Cao, JY Qiao, HY Huang, XY Fang, R Zhang… - Molecules, 2019 - mdpi.com
Icariin is a prenylated flavonol glycoside isolated from Epimedium herb, and has been
shown to be its main bioactive component. Recently, the antidepressant-like mechanism of …

Modulation of histone deacetylase, the ubiquitin proteasome system, and autophagy underlies the neuroprotective effects of venlafaxine in a rotenone-induced …

KA El-Saiy, RH Sayed, AE El-Sahar… - Chemico-Biological …, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease characterized by motor and non-
motor symptoms. Impairment of the ubiquitin proteasome system (UPS) and autophagy has …

Psychopharmacological properties and therapeutic profile of the antidepressant venlafaxine

B Coutens, A Yrondi, C Rampon, BP Guiard - Psychopharmacology, 2022 - Springer
Major depression (MD) is one of the most common psychiatric disorders worldwide.
Currently, the first-line treatment for MD targets the serotonin system but these drugs, notably …

Monitoring of emerging contaminants of concern in the aquatic environment: a review of studies showing the application of effect-based measures

A Yusuf, D O'Flynn, B White, L Holland… - Analytical …, 2021 - pubs.rsc.org
Water scarcity is increasingly a global cause of concern mainly due to widespread changes
in climate conditions and increased consumptive water use driven by the exponential …

Roflumilast ameliorates ovariectomy-induced depressive-like behavior in rats via activation of AMPK/mTOR/ULK1-dependent autophagy pathway

ES Zaki, RH Sayed, MA Saad, MF El-Yamany - Life sciences, 2023 - Elsevier
Aims Roflumilast, a well-known phosphodiesterase-4 (PDE-4) inhibitor, possess an anti-
inflammatory activity with approved indications in chronic obstructive pulmonary disease …

[HTML][HTML] Venlafaxine

D Singh, A Saadabadi - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
Venlafaxine - StatPearls - NCBI Bookshelf US flag An official website of the United States
government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Polymeric and electrospun patches for drug delivery through buccal route: Formulation and biointerface evaluation

G Mann, PM Gurave, A Kaul, KG Kadiyala… - Journal of Drug Delivery …, 2022 - Elsevier
Introduction Of the various transmucosal routes which are being considered for extended
and controlled drug delivery, buccal route is superior to other methods owing to high …

Resveratrol mitigates diclofenac‐induced hepatorenal toxicity in rats via modulation of miR‐144/Nrf2/GSH axis

EM Elbaz, KA Ahmed… - Journal of Biochemical …, 2022 - Wiley Online Library
Despite the extensive therapeutic uses of diclofenac, it may cause several adverse effects,
including hepatorenal injury. The antioxidant and anti‐inflammatory properties of resveratrol …