Zebrafish as an emerging model for osteoporosis: a primary testing platform for screening new osteo-active compounds

DJM Bergen, E Kague, CL Hammond - Frontiers in Endocrinology, 2019 - frontiersin.org
Osteoporosis is metabolic bone disease caused by an altered balance between bone
anabolism and catabolism. This dysregulated balance is responsible for fragile bones that …

Arachidonic acid matters

H Xu, X Meng, Y Wei, Q Ma, M Liang… - Reviews in …, 2022 - Wiley Online Library
Throughout the evolution of fish nutrition science, the importance of dietary arachidonic acid
(ARA, 20: 4n‐6) has been somewhat overlooked, likely due to the polarizing research focus …

[HTML][HTML] Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in develo** zebrafish

HJ Zhao, JK Xu, ZH Yan, HQ Ren, Y Zhang - Environment International, 2020 - Elsevier
Coexposure of MPs and other contaminants adsorbed from the environment has raised
many attentions, but the understanding of the combined effects of MPs and plastic additives …

The use of non-lethal sampling for transcriptomics to assess the physiological status of wild fishes

KM Jeffries, A Teffer, S Michaleski, NJ Bernier… - … and Physiology Part B …, 2021 - Elsevier
Fishes respond to different abiotic and biotic stressors through changes in gene expression
as a part of an integrated physiological response. Transcriptomics approaches have been …

Zebrafish models of human skeletal disorders: embryo and adult swimming together

M Carnovali, G Banfi, M Mariotti - BioMed Research …, 2019 - Wiley Online Library
Danio rerio (zebrafish) is an elective model organism for the study of vertebrate
development because of its high degree of homology with human genes and organs …

Melatonin is a potential drug for the prevention of bone loss during space flight

M Ikegame, A Hattori, MJ Tabata… - Journal of pineal …, 2019 - Wiley Online Library
Astronauts experience osteoporosis‐like loss of bone mass because of microgravity
conditions during space flight. To prevent bone loss, they need a riskless and antiresorptive …

Physiological consequences of space flight, including abnormal bone metabolism, space radiation injury, and circadian clock dysregulation: Implications of melatonin …

J Hirayama, A Hattori, A Takahashi… - Journal of pineal …, 2023 - Wiley Online Library
Exposure to the space environment induces a number of pathophysiological outcomes in
astronauts, including bone demineralization, sleep disorders, circadian clock dysregulation …

Alendronate rescued osteoporotic phenotype in a model of glucocorticoid‐induced osteoporosis in adult zebrafish scale

S Pasqualetti, T Congiu, G Banfi… - International journal of …, 2015 - Wiley Online Library
Long‐term effects of glucocorticoid treatment in humans induce bone loss and increase the
risk of fracture in the skeleton. The pathogenic mechanisms of glucocorticoid‐induced …

Repairing quite swimmingly: advances in regenerative medicine using zebrafish

W Goessling, TE North - Disease models & mechanisms, 2014 - journals.biologists.com
Regenerative medicine has the promise to alleviate morbidity and mortality caused by organ
dysfunction, longstanding injury and trauma. Although regenerative approaches for a few …