[HTML][HTML] The firmicutes/bacteroidetes ratio: a relevant marker of gut dysbiosis in obese patients?

F Magne, M Gotteland, L Gauthier, A Zazueta, S Pesoa… - Nutrients, 2020 - mdpi.com
The gut microbiota is emerging as a promising target for the management or prevention of
inflammatory and metabolic disorders in humans. Many of the current research efforts are …

Microbiome-wide association studies link dynamic microbial consortia to disease

JA Gilbert, RA Quinn, J Debelius, ZZ Xu, J Morton… - Nature, 2016 - nature.com
Rapid advances in DNA sequencing, metabolomics, proteomics and computational tools are
dramatically increasing access to the microbiome and identification of its links with disease …

EzBioCloud: a genome-driven database and platform for microbiome identification and discovery

M Chalita, YO Kim, S Park, HS Oh… - … of Systematic and …, 2024 - microbiologyresearch.org
With the continued evolution of DNA sequencing technologies, the role of genome
sequence data has become more integral in the classification and identification of Bacteria …

Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin

NA Bokulich, BD Kaehler, JR Rideout, M Dillon… - Microbiome, 2018 - Springer
Background Taxonomic classification of marker-gene sequences is an important step in
microbiome analysis. Results We present q2-feature-classifier (https://github. com/qiime2/q2 …

Characterization of the gut microbiome using 16S or shotgun metagenomics

J Jovel, J Patterson, W Wang, N Hotte… - Frontiers in …, 2016 - frontiersin.org
The advent of next generation sequencing (NGS) has enabled investigations of the gut
microbiome with unprecedented resolution and throughput. This has stimulated the …

Salicylic acid modulates colonization of the root microbiome by specific bacterial taxa

SL Lebeis, SH Paredes, DS Lundberg, N Breakfield… - Science, 2015 - science.org
Immune systems distinguish “self” from “nonself” to maintain homeostasis and must
differentially gate access to allow colonization by potentially beneficial, nonpathogenic …

Waste not, want not: why rarefying microbiome data is inadmissible

PJ McMurdie, S Holmes - PLoS computational biology, 2014 - journals.plos.org
Current practice in the normalization of microbiome count data is inefficient in the statistical
sense. For apparently historical reasons, the common approach is either to use simple …

A general species delimitation method with applications to phylogenetic placements

J Zhang, P Kapli, P Pavlidis, A Stamatakis - Bioinformatics, 2013 - academic.oup.com
Motivation: Sequence-based methods to delimit species are central to DNA taxonomy,
microbial community surveys and DNA metabarcoding studies. Current approaches either …

phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data

PJ McMurdie, S Holmes - PloS one, 2013 - journals.plos.org
Background The analysis of microbial communities through DNA sequencing brings many
challenges: the integration of different types of data with methods from ecology, genetics …

A review on the applications of next generation sequencing technologies as applied to food-related microbiome studies

Y Cao, S Fanning, S Proos, K Jordan… - Frontiers in …, 2017 - frontiersin.org
The development of next generation sequencing (NGS) techniques has enabled
researchers to study and understand the world of microorganisms from broader and deeper …