Cilia mediate an astonishing diversity of processes. Recent advances provide unexpected
insights into the regulatory mechanisms of cilium formation, and reveal diverse regulatory …

The primary cilium is an antenna-like, immotile organelle present on most types of
mammalian cells, which interprets extracellular signals that regulate growth and …

The centriole is an ancient microtubule-based organelle with a conserved nine-fold
symmetry. Centrioles form the core of centrosomes, which organize the interphase …

The cilium, once considered a vestigial structure, is a conserved, microtubule-based
organelle critical for transducing extracellular chemical and mechanical signals that control …

The primary cilium is an antenna-like organelle assembled on most types of quiescent and
differentiated mammalian cells. This immotile structure is essential for interpreting …

Although tumours initiate from oncogenic changes in a cancer cell, subsequent tumour
progression and therapeutic response depend on interactions between the cancer cells and …

Primary cilia, microtubule-based sensory structures, orchestrate various critical signals
during development and tissue homeostasis. In view of the rising interest into the reciprocal …

Primary cilia are solitary, microtubule-based structures emanating from the surface of most
vertebrate cells. Although it is understood that ciliary assembly and disassembly both …

The primary cilium, a sensory appendage that is present in most mammalian cells, plays
critical roles in signaling pathways and cell cycle progression. Mutations that affect the …

Abstract Background Kinesin superfamily (KIFs) has a long-reported significant influence on
the initiation, development, and progress of breast cancer. However, the prognostic value of …