Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs
SA Dilliard, DJ Siegwart - Nature Reviews Materials, 2023 - nature.com
Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of
medicines that directly reprogramme the central dogma of biology to prevent and treat …
medicines that directly reprogramme the central dogma of biology to prevent and treat …
mRNA-based cancer therapeutics
Due to the fact that mRNA technology allows the production of diverse vaccines and
treatments in a shorter time frame and with reduced expense compared to conventional …
treatments in a shorter time frame and with reduced expense compared to conventional …
Targeting drugs to tumours using cell membrane-coated nanoparticles
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …
specific nature, causing harm to non-malignant tissues. Over the past several decades …
Zwitterionic biomaterials
The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …
groups in their repeating units. When these oppositely charged groups are equally …
Minimally invasive nanomedicine: nanotechnology in photo-/ultrasound-/radiation-/magnetism-mediated therapy and imaging
Traditional treatments such as chemotherapy and surgery usually cause severe side effects
and excruciating pain. The emergence of nanomedicines and minimally invasive therapies …
and excruciating pain. The emergence of nanomedicines and minimally invasive therapies …
Functional graphdiyne for emerging applications: Recent advances and future challenges
M Wang, J Pu, Y Hu, Y Zi, ZG Wu… - Advanced Functional …, 2024 - Wiley Online Library
Graphdiyne (GDY) is regarded as an exceptional candidate to meet the growing demand in
many fields due to its rich chemical bonds, highly π‐conjugated structure, uniformly …
many fields due to its rich chemical bonds, highly π‐conjugated structure, uniformly …
Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
The tumor EPR effect for cancer drug delivery: Current status, limitations, and alternatives
Over the past three decades, the enhanced permeability and retention (EPR) effect has
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …
Nanomaterials for cancer therapy: current progress and perspectives
Cancer is a disease with complex pathological process. Current chemotherapy faces
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …
The future of drug delivery
Drug delivery technologies have been proven to improve treatment outcomes in many ways,
including enhancing therapeutic efficacy, reducing toxicity, increasing patient compliance …
including enhancing therapeutic efficacy, reducing toxicity, increasing patient compliance …