The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

The cascade of metastasis in tumor cells, exhibiting organ-specific tendencies, may occur at
numerous phases of the disease and progress under intense evolutionary pressures. Organ …

Over 90% of potential anti-cancer drug candidates results in translational failures in clinical
trials. The main reason for this failure can be attributed to the non-accurate pre-clinical …

Designer self‐assembling peptides form the entangled nanofiber networks in hydrogels by
ionic‐complementary self‐assembly. This type of hydrogel has realistic biological and …

Breast cancer is the most commonly diagnosed cancer in the USA. Although advances in
treatment over the past several decades have significantly improved the outlook for this …

The field of mechanobiology is gaining prominence due to recent findings that show cells
sense and respond to the mechanical properties of their environment through a process …

Cancer progression is associated with extensive remodeling of the tumor microenvironment
(TME), resulting in alterations of biochemical and biophysical cues that affect both cancer …

Decellularized extracellular matrix (dECM) is emerging as a valuable tool for generating 3D
in vitro tumor models that better recapitulate tumor-stroma interactions. However, the …

Solid cancers frequently relapse with distant metastasis, despite local and systemic
treatment. Cellular dormancy has been identified as an important mechanism underlying …

Dormancy is an evolutionarily conserved protective mechanism widely observed in nature. A
pathological example is found during cancer metastasis, where cancer cells disseminate …