Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse
functions in health and disease. Astrocyte dysfunction is found in numerous diseases …

The execution and learning of diverse movements involve neuronal networks distributed
throughout the nervous system. The brainstem and basal ganglia are key for processing …

The cerebellum, traditionally associated with motor coordination and balance, also plays a
crucial role in various aspects of higher-order function and dysfunction. Emerging research …

Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Parkinson disease (PD) is characterized by heterogeneous motor and non-motor symptoms,
resulting from neurodegeneration involving various parts of the central nervous system …

Historically, the thalamus has been viewed as little more than a relay, simply transferring
information to key players of the cast, the cortex and hippocampus, without providing any …

Multimodal evidence suggests that brain regions accumulate information over timescales
that vary according to anatomical hierarchy. Thus, these experimentally defined “temporal …

Both the cerebellum and the basal ganglia are known for their roles in motor control and
motivated behavior. These two systems have been classically considered as independent …

Natural products derived from plants, as well as their bioactive compounds, have been
extensively studied in recent years for their therapeutic potential in a variety of …

Given the key roles of the cerebellum in motor, cognitive, and affective operations and given
the decline of brain functions with aging, cerebellar circuitry is attracting the attention of the …