The tumor microenvironment (TME) demonstrates distinct hallmarks, including acidosis,
hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial …

The increasing number of infectious and chronic diseases, along with the rising healthcare
demand caused by an aging population, has led the scientific community to seek novel …

Targeted protein degradation has emerged as a novel therapeutic modality to treat human
diseases by utilizing the cell's own disposal systems to remove protein target. Significant …

Surgery is one of the most important paradigms for tumor therapy, while fluorescence
imaging (FI) offers real-time intraoperative guidance, greatly boosting treatment prognosis …

The traditional development of dyes for biological applications typically begins with
synthesis, is followed by spectroscopic/photophysical characterization, and culminates in …

Purpose Our study seeks to develop dual-modal organic-nanoagents for cancer therapy and
real-time fluorescence imaging, followed by their pre-clinical evaluation on a murine model …

Cancer is a major threat to human health; thus, early detection is imperative for successful
management. Rapid diagnosis can be achieved by imaging primary (subcutaneous) tumors …

Osteosarcoma (OS) is characterized by an unfavorable prognosis and high mortality rates,
with the local recurrence attributed to residual lesions post‐surgery being a major reason for …

Fluorescence imaging is a relatively new imaging method used to visualize different tissue
structures to help guide intraoperative operations, which has potential advantages with high …

Background Gastric cancer poses a major diagnostic and therapeutic challenge as surgical
resection provides the only opportunity for a cure. Specific labeling of gastric cancer could …