Autoimmune thyroid diseases

PP Ovčariček, R Görges, L Giovanella - Seminars in nuclear medicine, 2024 - Elsevier
Autoimmune thyroid diseases (AITDs) include a wide spectrum of thyroid diseases affecting
more commonly women than men. The most frequent forms are Graves' Disease (GD) and …

Immune checkpoint inhibitors-related thyroid dysfunction: epidemiology, clinical presentation, possible pathogenesis, and management

L Zhan, H Feng, H Liu, L Guo, C Chen… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are a group of drugs employed in the treatment of
various types of malignant tumors and improve the therapeutic effect. ICIs blocks negative co …

Thyroiditis: evaluation and treatment

BM Quintero, C Yazbeck, LB Sweeney - American family physician, 2021 - aafp.org
Thyroiditis is a general term for inflammation of the thyroid gland. The most common forms of
thyroiditis encountered by family physicians include Hashimoto, postpartum, and subacute …

Factors influencing the levothyroxine dose in the hormone replacement therapy of primary hypothyroidism in adults

P Caron, S Grunenwald, L Persani… - Reviews in Endocrine …, 2022 - Springer
Levothyroxine (LT4) is a safe, effective means of hormone replacement therapy for
hypothyroidism. Here, we review the pharmaceutical, pathophysiological and behavioural …

Increased risk of thyroid dysfunction by PD-1 and CTLA-4 blockade in patients without thyroid autoantibodies at baseline

S Iwama, T Kobayashi, Y Yasuda, T Okuji… - The Journal of …, 2022 - academic.oup.com
Background Previous studies showed that although the risk of thyroid dysfunction [thyroid
immune-related adverse events (irAEs)] induced by anti-programmed cell death-1 …

Combined use of tyrosine kinase inhibitors with PD-(L) 1 blockade increased the risk of thyroid dysfunction in PD-(L) 1 blockade: a prospective study

T Kobayashi, S Iwama, A Yamagami, T Izuchi… - Cancer Immunology …, 2024 - Springer
Background Anti-programmed cell death-1 (ligand-1) antibody [PD-(L) 1-Ab] can cause
destructive thyroiditis and/or hypothyroidism. In addition, tyrosine kinase inhibitors (TKIs) …

Structural Fusion of Natural and Synthetic Ligand Features Boosts RXR Agonist Potency

G Adouvi, F Nawa, M Ballarotto… - Journal of Medicinal …, 2023 - ACS Publications
The retinoid X receptors (RXRs) are ligand-activated transcription factors involved in, for
example, differentiation and apoptosis regulation. Currently used reference RXR agonists …

Biomarkers of fatigue in oncology: A systematic review

D Vanrusselt, C Sleurs, M Arif, J Lemiere… - Critical reviews in …, 2024 - Elsevier
Cancer-related fatigue (CRF) is a distressing side effect of cancer and treatment, affecting
both patients during active treatment and survivors, negatively impacting quality of life. While …

The use of levothyroxine absorption tests in clinical practice

P Caron, X Declèves - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Although levothyroxine (LT4) is a widely prescribed drug, more than 30% of LT4-treated
patients fail to achieve the recommended serum level of thyrotropin with a body weight …

[HTML][HTML] Effect of anti-COVID-19 drugs on patients with cancer

W Huang, W Liu, T Yu, Z Zhang, L Zhai… - European Journal of …, 2024 - Elsevier
The clinical treatment of patients with cancer who are also diagnosed with coronavirus
disease (COVID-19) has been a challenging issue since the outbreak of COVID-19 …