Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

Glycosylation, the addition of glycans or carbohydrates to proteins, lipids, or other glycans, is
a complex post-translational modification that plays a crucial role in cellular function. It is …

Multiple sclerosis (MS) is the inflammatory demyelinating and neurodegenerative disease of
the central nervous system (CNS) that affects approximately 2.8 million people worldwide. In …

Glycans are carbohydrates that are made by all organisms and covalently conjugated to
other biomolecules. Glycans cover the surface of both human cells and pathogens and are …

All four subclasses of immunoglobulin G (IgG) antibodies have glycan structures attached to
the protein part of the IgG molecules. Glycans linked to the Fc portion of IgG are found in all …

The effective treatment of autoimmune disorders can greatly benefit from disease-specific
biomarkers that are functionally involved in immune system regulation and can be collected …

Abstract Ecto‐5′‐nucleotidase/CD73 (eN/CD73) is a membrane‐bound enzyme involved
in extracellular production of adenosine and a cell adhesion molecule involved in cell–cell …

Serum haptoglobin (Hp), a highly sialylated biomolecule with four N‐glycosylation sites, is a
positive acute‐phase response glycoprotein that acts as an immunomodulator. Hp has …

Autoimmune diseases are accompanied by changes in protein glycosylation, in both the
immune system and target tissues. The best-studied alteration in autoimmunity is …

Bacteremia—ie, the presence of pathogens in the blood stream—is associated with long-
term morbidity and is a potential precursor condition to life-threatening sepsis. Timely …