Association between heavy metal exposure and Parkinson's disease: a review of the mechanisms related to oxidative stress

S Pyatha, H Kim, D Lee, K Kim - Antioxidants, 2022 - mdpi.com
Parkinson's disease (PD) is a gradually progressing neurodegenerative condition that is
marked by a loss of motor coordination along with non-motor features. Although the precise …

Role of heavy metals (copper (Cu), arsenic (As), cadmium (Cd), iron (Fe) and lithium (Li)) induced neurotoxicity

B Vellingiri, A Suriyanarayanan, P Selvaraj… - Chemosphere, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative condition characterized by the dopamine
(DA) neuronal loss in the substantia nigra. PD impairs motor controls symptoms such as …

Systematic review: quantitative susceptibility map** (QSM) of brain iron profile in neurodegenerative diseases

P Ravanfar, SM Loi, WT Syeda… - Frontiers in …, 2021 - frontiersin.org
Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

Iron deposition in parkinson's disease: A mini-review

W Zeng, J Cai, L Zhang, Q Peng - Cellular and molecular neurobiology, 2024 - Springer
Iron deposition is crucial pathological changes observed in patients with Parkinson's
disease (PD). Recently, scientists have actively explored therapeutic approaches targeting …

Ferroptosis was more initial in cell death caused by iron overload and its underlying mechanism in Parkinson's disease

P Zhang, L Chen, Q Zhao, X Du, M Bi, Y Li… - Free Radical Biology …, 2020 - Elsevier
Ferroptosis, an iron-dependent nonapoptotic cell death, was referred in neurodegenerative
diseases, but its role in Parkinson's disease remains unclear. Here, we used ferric …

Metals and Parkinson's disease: mechanisms and biochemical processes

G Bjorklund, V Stejskal, MA Urbina… - Current Medicinal …, 2018 - benthamdirect.com
Genetic background accounts for only 5 to 10% of the reported cases of Parkinson's disease
(PD), while the remaining cases are of unknown etiology. It is believed that environmental …

[HTML][HTML] Neuroimaging of Parkinson's disease by quantitative susceptibility map**

X Guan, M Lancione, S Ayton, P Dusek… - NeuroImage, 2024 - Elsevier
Parkinson's disease (PD) is a common neurodegenerative disease, and apart from a few
rare genetic causes, its pathogenesis remains largely unclear. Recent scientific interest has …

Iron deposition in Parkinson's disease by quantitative susceptibility map**

Q Chen, Y Chen, Y Zhang, F Wang, H Yu, C Zhang… - BMC neuroscience, 2019 - Springer
Abstract Background Patients with Parkinson's disease (PD) have elevated levels of brain
iron, especially in the nigrostriatal dopaminergic system. The purpose of this study was to …

MAO inhibitors and their wider applications: a patent review

S Carradori, D Secci, JP Petzer - Expert opinion on therapeutic …, 2018 - Taylor & Francis
Introduction: Monoamine oxidase (MAO) inhibitors, after the initial 'golden age', are currently
used as third-line antidepressants (selective MAO-A inhibitors) or clinically enrolled as co …

Ferroptosis and traumatic brain injury

Z Geng, Z Guo, R Guo, R Ye, W Zhu, B Yan - Brain Research Bulletin, 2021 - Elsevier
Traumatic brain injury (TBI) is a worldwide health problem contributing to significant
economic burden. TBI is difficult to treat partly due to incomplete understanding of …