A guide to assessing cellular senescence in vitro and in vivo

E González‐Gualda, AG Baker, L Fruk… - The FEBS …, 2021 - Wiley Online Library
Cellular senescence is a physiological mechanism whereby a proliferating cell undergoes a
stable cell cycle arrest upon damage or stress and elicits a secretory phenotype. This highly …

Activatable senoprobes and senolytics: Novel strategies to detect and target senescent cells

S Morsli, GJ Doherty, D Muñoz-Espín - Mechanisms of Ageing and …, 2022 - Elsevier
Pharmacologically active compounds that manipulate cellular senescence (senotherapies)
have recently shown great promise in multiple pre-clinical disease models, and some of …

Current and potential roles of immuno-PET/-SPECT in CAR T-cell therapy

A Mulgaonkar, D Udayakumar, Y Yang, S Harris… - Frontiers in …, 2023 - frontiersin.org
Chimeric antigen receptor (CAR) T-cell therapies have evolved as breakthrough treatment
options for the management of hematological malignancies and are also being developed …

[КНИГА][B] Cellular senescence in disease

M Serrano, D Munoz-Espin - 2021 - books.google.com
Winner of the 2023 PROSE award in Biomedicine and Neuroscience! Research in the field
of senescence has boomed recently due to the gradual realization that senescent cells are …

Novel probes and carriers to target senescent cells

B Lozano-Torres, JF Blandez, F Sancenón… - Senolytics in Disease …, 2020 - Springer
Detecting senescent cells has become a task of increasing importance in recent years. The
implication of cellular senescence in a variety of physiological processes as well as in …

In Vivo Monitoring of Cellular Senescence by Photoacoustic and Fluorescence Imaging Utilizing a Nanostructured Organic Probe

AG Baker, HL Ou, M Hartono, AB Popov, EL Brown… - bioRxiv, 2023 - biorxiv.org
Senescent cells accumulate in multiple age-related disorders, including cancer,
exacerbating the pathological manifestations, and the eradication of these cells has …