Neutrophils in cancer
LW Treffers, IH Hiemstra, TW Kuijpers… - Immunological …, 2016 - Wiley Online Library
Neutrophils play an important role in cancer. This does not only relate to the well‐
established prognostic value of the presence of neutrophils, either in the blood or in tumor …
established prognostic value of the presence of neutrophils, either in the blood or in tumor …
Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets
Extracellular matrix (ECM) molecules are responsible for structural and biochemical support,
as well as for regulation of molecular signalling and tissue repair in many organ structures …
as well as for regulation of molecular signalling and tissue repair in many organ structures …
SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile
Background The immune response to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection in COVID-19 patients has been extensively investigated. However …
(SARS-CoV-2) infection in COVID-19 patients has been extensively investigated. However …
Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor
Aspirin (ASA) and dexamethasone (DEX) are widely used anti-inflammatory agents yet their
mechanism (s) for blocking polymorphonuclear neutrophil (PMN) accumulation at sites of …
mechanism (s) for blocking polymorphonuclear neutrophil (PMN) accumulation at sites of …
The role of neutrophil elastase in acute lung injury
K Kawabata, T Hagio, S Matsuoka - European journal of pharmacology, 2002 - Elsevier
Beside its physiological function as a powerful host defense, neutrophil elastase is also
known as one of the most destructive enzymes in the body. Current notion holds that …
known as one of the most destructive enzymes in the body. Current notion holds that …
Serine proteases of the human immune system in health and disease
Serine proteases form a large family of protein-cleaving enzymes that play an essential role
in processes like blood coagulation, apoptosis and inflammation. Immune cells express a …
in processes like blood coagulation, apoptosis and inflammation. Immune cells express a …
Leukocyte elastase: physiological functions and role in acute lung injury
WL Lee, GP Downey - American journal of respiratory and critical …, 2001 - atsjournals.org
Cytotoxicity and Wound Healing Evidence for the Role of Elastase in ARDS in Humans
Animal Models of Lung Injury and Leukocyte Elastase Studies of Protease Inhibitors and …
Animal Models of Lung Injury and Leukocyte Elastase Studies of Protease Inhibitors and …
Two faces of chondroitin sulfate proteoglycan in spinal cord repair: a role in microglia/macrophage activation
A Rolls, R Shechter, A London, Y Segev… - PLoS …, 2008 - journals.plos.org
Background Chondroitin sulfate proteoglycan (CSPG) is a major component of the glial scar.
It is considered to be a major obstacle for central nervous system (CNS) recovery after injury …
It is considered to be a major obstacle for central nervous system (CNS) recovery after injury …
Extracellular matrix moieties, cytokines, and enzymes: dynamic effects on immune cell behavior and inflammation
GG Vaday, O Lider - Journal of leukocyte biology, 2000 - Wiley Online Library
Tissue injury caused by infection or physical damage evokes inflammatory reactions and
events that are necessary for regaining homeostasis. Central to these events is the …
events that are necessary for regaining homeostasis. Central to these events is the …
Rapid and efficient homing of human CD34+CD38−/lowCXCR4+stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2mnull …
Stem cell homing into the bone microenvironment is the first step in the initiation of marrow-
derived blood cells. It is reported that human severe combined immunodeficient (SCID) …
derived blood cells. It is reported that human severe combined immunodeficient (SCID) …