Histology permits the observation of otherwise invisible structures of the internal topography
of a specimen. Although it enables the investigation of tissues at a cellular level, it is invasive …

Introduction Spread through air spaces (STAS) is a method of invasion in lung
adenocarcinoma and is associated with tumor recurrence and poor survival. The spatial …

Background In biomedical research, a huge variety of different techniques is currently
available for the structural examination of small specimens, including conventional light …

Synchrotron radiation micro-computed tomography (SRµCT) based virtual histology, in
combination with dedicated ex vivo staining protocols and/or phase contrast, is an emerging …

Achilles tendons are mechanosensitive, and their complex hierarchical structure is in part
the result of the mechanical stimulation conveyed by the muscles. To fully understand how …

Modern imaging and dissemination methods enable morphologists to share complex, three-
dimensional (3D) data in ways not previously possible. Here we present a 3D interactive …

Background: Three-dimensional (3D)-reconstruction from paraffin embedded sections has
been considered laborious and time-consuming. However, the high-resolution images of …

Background: The Portable Document Format (PDF) is the standard file format for the
communication of biomedical information via the internet and for electronic scholarly …

Dual‐energy computed tomography (DECT) uses two different x‐ray energy spectra in order
to differentiate between tissues, materials or elements in a single sample or patient. DECT is …

The use of volume data and digital three-dimensional (3D) surface models in biology has
increased quickly and steadily. Various methods are available to acquire 3D data, among …