The autonomic nervous system modulates glucose and fat metabolism through both direct
neural effects and hormonal effects. This review presents recent concepts on the …

Liver glycogen is synthesized after a meal in response to an increase in blood glucose
concentration in the portal vein and endocrine and neuroendocrine signals, and is degraded …

The biologic and chemical properties of alkylresorcinols (ARs) have been reviewed
previously, but there has been relatively little research or focus on the importance of ARs in …

The fat‐derived hormone, leptin, is well known to regulate body weight. However, there is
now substantial evidence that leptin also plays a primary role in the regulation of glucose …

Although many effects of leptin are mediated through the central nervous system, leptin can
regulate metabolism through a direct action on peripheral tissues, such as fat and liver. We …

Leptin is a 16-kDa hormone secreted by adipocytes and plays an important role in control of
feeding behavior and energy expenditure. In obesity, circulating levels of leptin and insulin …

Excess of body fat, or obesity, is a major health problem and confers a higher risk of
cardiovascular and metabolic disorders such as diabetes, hypertension, and coronary heart …

Objectives Obesity is a major risk factor in aetiology of type 2 diabetes mellitus (T2DM).
Leptin (LEP) is an anti-obesity hormone which regulates food intake, energy expenditure …

The discovery of the obese gene product, leptin has generated enormous interest in how the
periphery signals the status of nutritional stores to specific hypothalamic nuclei involved in …

Introduction: Leptin action is a dynamic area of investigation that continues to broaden
beyond the basic lipostatic model originally envisaged. Here, we show that leptin is …