Chagas disease
JA Pérez-Molina, I Molina - The Lancet, 2018 - thelancet.com
Chagas disease is an anthropozoonosis from the American continent that has spread from
its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi …
its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi …
Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American Heart Association
Background: Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …
Randomized trial of benznidazole for chronic Chagas' cardiomyopathy
CA Morillo, JA Marin-Neto, A Avezum… - … England Journal of …, 2015 - Mass Medical Soc
Background The role of trypanocidal therapy in patients with established Chagas'
cardiomyopathy is unproven. Methods We conducted a prospective, multicenter …
cardiomyopathy is unproven. Methods We conducted a prospective, multicenter …
Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity
B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
The WHO recognizes human African trypanosomiasis, Chagas disease and the
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
Pathology and pathogenesis of Chagas heart disease
KM Bonney, DJ Luthringer, SA Kim… - Annual Review of …, 2019 - annualreviews.org
Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately
one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T …
one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T …
Chagas disease drug discovery: toward a new era
E Chatelain - Journal of biomolecular screening, 2015 - journals.sagepub.com
American trypanosomiasis, or Chagas disease, is the result of infection by the Trypanosoma
cruzi parasite. Endemic in Latin America where it is the major cause of death from …
cruzi parasite. Endemic in Latin America where it is the major cause of death from …
Discrete ty** units of Trypanosoma cruzi: Geographical and biological distribution in the Americas
Chagas disease caused by Trypanosoma cruzi is a public health issue in Latin America.
This highly diverse parasite is divided into at least seven discrete ty** units (DTUs) TcI …
This highly diverse parasite is divided into at least seven discrete ty** units (DTUs) TcI …
Worldwide control and management of Chagas disease in a new era of globalization: a close look at congenital Trypanosoma cruzi infection
A Abras, C Ballart, A Fernández-Arévalo… - Clinical microbiology …, 2022 - Am Soc Microbiol
Population movements have turned Chagas disease (CD) into a global public health
problem. Despite the successful implementation of subregional initiatives to control vectorial …
problem. Despite the successful implementation of subregional initiatives to control vectorial …
Parasite zoonoses and wildlife: one health, spillover and human activity
RCA Thompson - International journal for parasitology, 2013 - Elsevier
This review examines parasite zoonoses and wildlife in the context of the One Health triad
that encompasses humans, domestic animals, wildlife and the changing ecosystems in …
that encompasses humans, domestic animals, wildlife and the changing ecosystems in …