A review on chitosan and its development as pulmonary particulate anti-infective and anti-cancer drug carriers

RM Rasul, MT Muniandy, Z Zakaria, K Shah… - Carbohydrate …, 2020 - Elsevier
Chitosan, as a biodegradable and biocompatible polymer, is characterized by anti-microbial
and anti-cancer properties. It lately has received a widespread interest for use as the …

Pulmonary drug delivery systems for tuberculosis treatment

DD Pham, E Fattal, N Tsapis - International journal of pharmaceutics, 2015 - Elsevier
Tuberculosis (TB) remains a major global health problem as it is the second leading cause
of death from an infectious disease worldwide, after the human immunodeficiency virus …

Inhaled drug therapy for treatment of tuberculosis

A Misra, AJ Hickey, C Rossi, G Borchard, H Terada… - Tuberculosis, 2011 - Elsevier
The lungs have received attention as a portal for drug delivery in tuberculosis (TB) from
researchers addressing diverse objectives. These include:(a) targeting alveolar …

Rifabutin loaded inhalable β-glucan microparticle based drug delivery system for pulmonary TB

F Ahmad, S Ahmad, TK Upadhyay, S Singh… - Scientific Reports, 2024 - nature.com
Inhalable microparticle-based anti TB drug delivery systems are being investigated
extensively for Tuberculosis [TB] treatment as they offer efficient and deep lung deposition …

Dry powder inhalers of antitubercular drugs

N Nainwal, Y Sharma, V Jakhmola - Tuberculosis, 2022 - Elsevier
Despite advancements in the medical and pharmaceutical fields, tuberculosis remains a
major health problem globally. Patients do not widely accept the conventional approach to …

Dry powder inhalable formulations for anti-tubercular therapy

T Parumasivam, RYK Chang, S Abdelghany… - Advanced drug delivery …, 2016 - Elsevier
Tuberculosis (TB) is an intracellular infectious disease caused by the airborne bacterium,
Mycobacterium tuberculosis. Despite considerable research efforts, the treatment of TB …

Inhaled drug treatment for tuberculosis: Past progress and future prospects

AJ Hickey, PG Durham, A Dharmadhikari… - Journal of Controlled …, 2016 - Elsevier
Since the 1990s the rising incidence of multiple drug resistant TB, particularly in the context
of human immunodeficiency virus co-infected patients, has threatened global TB control. At …

Critical physicochemical and biological attributes of nanoemulsions for pulmonary delivery of rifampicin by nebulization technique in tuberculosis treatment

K Shah, LW Chan, TW Wong - Drug delivery, 2017 - Taylor & Francis
The study investigated aerosolization, pulmonary inhalation, intracellular trafficking potential
in macrophages and pharmacokinetics profiles of rifampicin-oleic acid first-generation …

A novel dry powder inhalable formulation incorporating three first-line anti-tubercular antibiotics

JGY Chan, HK Chan, CA Prestidge, JA Denman… - European Journal of …, 2013 - Elsevier
Treatment for tuberculosis (TB) using the standard oral antibiotic regimen is effective but
inefficient, requiring high drug dosing and lengthy treatment times. Three concurrent first-line …

[HTML][HTML] Preparation and characterization of beta-glucan particles containing a payload of nanoembedded rifabutin for enhanced targeted delivery to macrophages

TK Upadhyay, N Fatima, D Sharma… - EXCLI …, 2017 - ncbi.nlm.nih.gov
Abstract β-glucan particles (GP) are polymeric carbohydrates, mainly found as components
of cell wall fungi, yeast, bacteria and also in cereals such as barley and oat, and have been …