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[HTML][HTML] Potential herb–drug interactions between anti-COVID-19 drugs and traditional Chinese medicine
L Ye, S Fan, P Zhao, C Wu, M Liu, S Hu, P Wang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …
An exhaustive comprehension of the role of herbal medicines in Pre-and Post-COVID manifestations
Ethnopharmacological relevance The coronavirus disease (COVID-19) has relentlessly
spread all over the world even after the advent of vaccines. It demands management …
spread all over the world even after the advent of vaccines. It demands management …
An in silico-in vitro antimalarial and antimicrobial investigation of newer 7-chloroquinoline based Schiff-bases
Abstract New fifteen 7-chloroquinolines (M1a-o) were synthesized by microwave irradiation
and conventional route via Schiff-base reaction. The key intermediate 4-((7-chloroquinolin-4 …
and conventional route via Schiff-base reaction. The key intermediate 4-((7-chloroquinolin-4 …
Design, synthesis, in vitro anticancer and antimicrobial evaluation, SAR analysis, molecular docking and dynamic simulation of new pyrazoles, triazoles and …
HA Radwan, I Ahmad, IMM Othman… - Journal of Molecular …, 2022 - Elsevier
A new series of pyrazoles, triazoles and pyridazines based isoxazole were synthesized, and
well characterized. Their antibacterial, antifungal and cytotoxic activities were successfully …
well characterized. Their antibacterial, antifungal and cytotoxic activities were successfully …
Design, synthesis, molecular modeling, DFT, ADME and biological evaluation studies of some new 1, 3, 4-oxadiazole linked benzimidazoles as anticancer agents and …
Breast cancer is the most frequent female cancer and second cause of cancer-related
deaths among women around the world. Two thirds of breast cancer patients have hormone …
deaths among women around the world. Two thirds of breast cancer patients have hormone …
Design, synthesis, molecular docking and molecular dynamics studies of novel triazolothiadiazine derivatives containing furan or thiophene rings as anticancer agents
Breast cancer is the most common cancer type amoung post-menopausal women.
Aromatase inhibitors were used in the treatment of patients. However, drug resistance may …
Aromatase inhibitors were used in the treatment of patients. However, drug resistance may …
Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors
The inhibitory action of fifteen benzyloxy ortho/para-substituted chalcones (B1-B15) was
evaluated against human monoamine oxidases (hMAOs). All the molecules inhibited hMAO …
evaluated against human monoamine oxidases (hMAOs). All the molecules inhibited hMAO …
In-vitro anticancer evaluation of newly designed and characterized tri/tetra-substituted imidazole congeners-maternal embryonic leucine zipper kinase inhibitors …
Our cascading attempt to develop new potent molecules now involves designing a series of
imidazole derivatives and synthesizing two sets of 2, 4, 5-tri-substituted (4a–4d) and 1, 2, 4 …
imidazole derivatives and synthesizing two sets of 2, 4, 5-tri-substituted (4a–4d) and 1, 2, 4 …
[HTML][HTML] Design, synthesis, biological evaluation and in silico studies of novel 1, 2, 3-triazole linked benzoxazine-2, 4-dione conjugates as potent antimicrobial …
MB Hammouda, I Ahmad, A Hamdi, A Dbeibia… - Arabian Journal of …, 2022 - Elsevier
In an attempt to rationalize the search for new potential anti-inflammatory and anti-infection
agents, a new series of 1, 4-and 1, 5-disubstituted 1, 2, 3-triazoles linked benzoxazine …
agents, a new series of 1, 4-and 1, 5-disubstituted 1, 2, 3-triazoles linked benzoxazine …
A comprehensive study to unleash the putative inhibitors of serotype2 of dengue virus: insights from an in silico structure-based drug discovery
Dengue fever is a mosquito-borne disease that claims the lives of millions of people around
the world. A number of factors like disease's non-specific symptoms, increased viral …
the world. A number of factors like disease's non-specific symptoms, increased viral …