The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles
Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall, continually
exposed to mechanical signals and biochemical components generated in the blood …
exposed to mechanical signals and biochemical components generated in the blood …
Dextromethorphan mediated bitter taste receptor activation in the pulmonary circuit causes vasoconstriction
Activation of bitter taste receptors (T2Rs) in human airway smooth muscle cells leads to
muscle relaxation and bronchodilation. This finding led to our hypothesis that T2Rs are …
muscle relaxation and bronchodilation. This finding led to our hypothesis that T2Rs are …
[HTML][HTML] Carvacrol protects against diabetes-induced hypercontractility in the aorta through activation of the PI3K/Akt pathway
Y Liu, J Wei, KT Ma, CL Li, YP Mai, XX Qiu… - Biomedicine & …, 2020 - Elsevier
Vascular complications induced by diabetes constitute the principal cause of morbidity and
mortality in diabetic patients. It has been reported that carvacrol (CAR) possesses a wide …
mortality in diabetic patients. It has been reported that carvacrol (CAR) possesses a wide …
Characterization of human vocal fold fibroblasts derived from chronic scar
Abstract Objectives/Hypothesis: In vitro modeling of cell‐matrix interactions that occur during
human vocal fold scarring is uncommon, as primary human vocal fold scar fibroblast cell …
human vocal fold scarring is uncommon, as primary human vocal fold scar fibroblast cell …
Osteoprotegerin deficiency limits angiotensin II–induced aortic dilatation and rupture in the apolipoprotein E–knockout mouse
CS Moran, RJ Jose, E Biros… - … , thrombosis, and vascular …, 2014 - Am Heart Assoc
Objective—Mounting evidence links osteoprotegerin with cardiovascular disease. Elevated
serum and aortic tissue osteoprotegerin are associated with the presence and growth of …
serum and aortic tissue osteoprotegerin are associated with the presence and growth of …
Emerging role of angiotensin type 2 receptor (AT2R)/Akt/NO pathway in vascular smooth muscle cell in the hyperthyroidism
Hyperthyroidism is characterized by increased vascular relaxation and decreased vascular
contraction and is associated with augmented levels of triiodothyronine (T3) that contribute …
contraction and is associated with augmented levels of triiodothyronine (T3) that contribute …
[HTML][HTML] Phenotypic modulation of mesenteric vascular smooth muscle cells from type 2 diabetic rats is associated with decreased caveolin-1 expression
MA Carrillo-Sepulveda, T Matsumoto - Cellular Physiology and …, 2014 - karger.com
Aims: Diabetes-induced vascular complications are associated with vascular smooth muscle
cell (VSMC) phenotypic modulation, switching from a contractile to a synthetic-proliferative …
cell (VSMC) phenotypic modulation, switching from a contractile to a synthetic-proliferative …
miR‐217 alleviates high‐glucose‐induced vascular smooth muscle cell dysfunction via regulating ROCK1
W Zhou, S Ye, W Wang - Journal of Biochemical and Molecular …, 2021 - Wiley Online Library
Abstract MicroRNA‐217 (miR‐217) has been recently reported to be abnormally expressed
during atherosclerosis. Nonetheless, it still remains unknown whether miR‐217 can regulate …
during atherosclerosis. Nonetheless, it still remains unknown whether miR‐217 can regulate …
[HTML][HTML] Angiotensin (1-7) inhibits Ang II-mediated ERK1/2 activation by stimulating MKP-1 activation in vascular smooth muscle cells
A Sousa-Lopes, RA de Freitas… - … Journal of Molecular …, 2020 - ncbi.nlm.nih.gov
The renin–angiotensin system (RAS) exerts profound physiological effects on blood
pressure regulation and fluid homeostasis, mainly by modulating renal, cardiovascular, and …
pressure regulation and fluid homeostasis, mainly by modulating renal, cardiovascular, and …
Modulation of Kinin B2 Receptor Signaling Controls Aortic Dilatation and Rupture in the Angiotensin II–Infused Apolipoprotein E–Deficient Mouse
Objective—Abdominal aortic aneurysm (AAA) is an important cause of mortality in older
adults. Activity of the local kallikrein–kinin system may be important in cardiovascular …
adults. Activity of the local kallikrein–kinin system may be important in cardiovascular …