[HTML][HTML] Indole derivatives: a versatile scaffold in modern drug discovery—an updated review on their multifaceted therapeutic applications (2020–2024)
Indole derivatives have become an important class of compounds in medicinal chemistry,
recognized for their wide-ranging biological activities and therapeutic potential. This review …
recognized for their wide-ranging biological activities and therapeutic potential. This review …
Comprehensive coverage on anti-mycobacterial endeavour reported during 2022
TM Dhameliya, DD Vekariya, HY Patel… - European Journal of …, 2023 - Elsevier
TB being one of the deadliest diseases and second most common infectious cause of
deaths, poses the severe threat to global health. The extended duration of therapy owing to …
deaths, poses the severe threat to global health. The extended duration of therapy owing to …
A quinquennial review on recent advancements and developments in search of anti-malarial agents
TM Dhameliya, D Kathuria, TM Patel… - Current Topics in …, 2023 - benthamdirect.com
Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …
estimated to kill between one and two million people (mainly children) every year. Novel anti …
In silico drug design strategies for discovering novel tuberculosis therapeutics
Introduction Tuberculosis remains a significant concern in global public health due to its
intricate biology and propensity for develo** antibiotic resistance. Discovering new drugs …
intricate biology and propensity for develo** antibiotic resistance. Discovering new drugs …
Synthesis of novel indole-oxindole clubbed 1, 2, 3-triazole hybrids: antimicrobial evaluation and molecular docking study
A new series of indole-oxindole clubbed 1, 2, 3-triazole hybrids 5 (a–o) was thoughtfully
designed and synthesized via Cu-catalysed azide-alkyne cycloaddition (CuAAC) click …
designed and synthesized via Cu-catalysed azide-alkyne cycloaddition (CuAAC) click …
Novel strategies based on natural products and synthetic derivatives to overcome resistance in Mycobacterium tuberculosis
One of the biggest health challenges of today's world is the emergence of antimicrobial
resistance (AMR), which renders conventional therapeutics insufficient and urgently …
resistance (AMR), which renders conventional therapeutics insufficient and urgently …
Develo** novel indoles as antitubercular agents and simulated annealing-based analysis of their binding with MmpL3
Aim This research aimed to develop novel indole-2-carboxamides as potential
antitubercular agents using rational drug design. It also focused on identifying the critical …
antitubercular agents using rational drug design. It also focused on identifying the critical …
Design, synthesis and pharmacological evaluation of novel thiazole derivatives as c-Met kinase inhibitors and anticancer agents
In search of novel anticancer agents, the design and synthesis of novel sixteen thiazole
derivatives (7a-p) have been reported along with their characterization using 1 H NMR, 13 C …
derivatives (7a-p) have been reported along with their characterization using 1 H NMR, 13 C …
Indole Derivatives as Promising Anti‐Dengue Agents: A Review of Recent Advances
MAP Januário, COR Junior… - Chemistry & …, 2024 - Wiley Online Library
Dengue, a mosquito‐borne disease transmitted by Aedes mosquitoes, is a significant global
health concern. Despite extensive research, effective treatments remain limited. The indole …
health concern. Despite extensive research, effective treatments remain limited. The indole …
Synthetic account on indoles and their analogues as potential anti-plasmodial agents
TM Dhameliya, DD Vekariya, PR Bhatt, T Kachroo… - Molecular Diversity, 2024 - Springer
Malaria caused by P. falciparum, has been recognized as one of the major infectious
diseases causing the death of several patients as per the reports from the World Health …
diseases causing the death of several patients as per the reports from the World Health …