Staphylococcus aureus host interactions and adaptation

BP Howden, SG Giulieri, T Wong Fok Lung… - Nature Reviews …, 2023‏ - nature.com
Invasive Staphylococcus aureus infections are common, causing high mortality,
compounded by the propensity of the bacterium to develop drug resistance. S. aureus is an …

Methicillin-resistant Staphylococcus aureus

AS Lee, H De Lencastre, J Garau… - Nature reviews Disease …, 2018‏ - nature.com
Since the 1960s, methicillin-resistant Staphylococcus aureus (MRSA) has emerged,
disseminated globally and become a leading cause of bacterial infections in both health …

Staphylococcus aureus bloodstream infections: pathogenesis and regulatory mechanisms

JM Kwiecinski, AR Horswill - Current opinion in microbiology, 2020‏ - Elsevier
Highlights•Phagocytes play both protective and detrimental roles in containing bloodstream
S. aureus.•S. aureus hijacks the host coagulation system and uses it to bind host …

[HTML][HTML] Burden of bacterial bloodstream infection—a brief update on epidemiology and significance of multidrug-resistant pathogens

WV Kern, S Rieg - Clinical Microbiology and Infection, 2020‏ - Elsevier
Background Bloodstream infections comprise a wide variety of pathogens and clinical
syndromes with considerable overlap with similar syndromes of non-bacteraemic infections …

Correlation Between Biofilm-Formation and the Antibiotic Resistant Phenotype in Staphylococcus aureus Isolates: A Laboratory-Based Study in Hungary and a …

SA Senobar Tahaei, A Stájer, I Barrak… - Infection and drug …, 2021‏ - Taylor & Francis
Introduction Staphylococcus aureus (S. aureus) is an important causative pathogen in
human infections. The production of biofilms by bacteria is an important factor, leading to …

Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates

A Papkou, J Hedge, N Kapel, B Young… - Nature …, 2020‏ - nature.com
The rise of antibiotic resistance in many bacterial pathogens has been driven by the spread
of a few successful strains, suggesting that some bacteria are genetically pre-disposed to …

Virulence attributes of successful methicillin-resistant Staphylococcus aureus lineages

JH Jiang, DR Cameron, C Nethercott… - Clinical microbiology …, 2023‏ - journals.asm.org
Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of severe and often
fatal infections. MRSA epidemics have occurred in waves, whereby a previously successful …

[PDF][PDF] Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis

A Buitrago-Lopez, J Sanderson, L Johnson… - Bmj, 2011‏ - bmj.com
Objective To evaluate the association of chocolate consumption with the risk of develo**
cardiometabolic disorders. Design Systematic review and meta-analysis of randomised …

Characterisation of antibiotic resistance, virulence, clonality and mortality in MRSA and MSSA bloodstream infections at a tertiary-level hospital in Hungary: a 6-year …

A Horváth, O Dobay, J Sahin-Tóth, E Juhász… - Annals of clinical …, 2020‏ - Springer
Background Staphylococcus aureus bloodstream infections (BSI) cause significant morbidity
and mortality due to the frequent antibiotic resistance, toxin and adhesin production of the …

Forest and trees: exploring bacterial virulence with genome-wide association studies and machine learning

JP Allen, E Snitkin, NB Pincus, AR Hauser - Trends in microbiology, 2021‏ - cell.com
The advent of inexpensive and rapid sequencing technologies has allowed bacterial whole-
genome sequences to be generated at an unprecedented pace. This wealth of information …