Protein misfolding and aggregation, a key contributor to the progression of numerous
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …

Dissolved organic matter (DOM) exists ubiquitously in environments and plays critical roles
in pollutant mitigation, transformation, and organic geochemical cycling. Understanding its …

The production of active pharmaceutical ingredients (APIs) is currently undergoing its
biggest transformation in a century. The changes are based on the rapid and dramatic …

The transition to continuous biomanufacturing is considered the next step to reduce costs
and improve process robustness in the biopharmaceutical industry, while also improving …

Raman spectroscopy has the potential to revolutionise many aspects of biopharmaceutical
process development. The widespread adoption of this promising technology has been …

Rapid release of biopharmaceutical products enables a more efficient drug manufacturing
process. Multi-attribute methods that target several product quality attributes (PQAs) at one …

A comprehensive survey review of new and noteworthy developments of 2D correlation
spectroscopy (2DCOS) and its applications for the last two years is compiled. This review …

In this study, we designed and prepared a trastuzumab-coupled drug delivery system with
pH response characteristics using mesoporous zeolitic imidazolate framework-8 (ZIF-8) as …

In the last decade, a number of studies have successfully demonstrated Raman
spectroscopy as an emerging analytical technique for monitoring antibody aggregation …

Lot release and stability testing of biologics are essential parts of the quality control strategy
for ensuring therapeutic material dosed to patients is safe and efficacious, and consistent …