Microglia polarization from M1 to M2 in neurodegenerative diseases

S Guo, H Wang, Y Yin - Frontiers in aging neuroscience, 2022‏ - frontiersin.org
Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases
such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …

Association between psychosocial stress and hypertension: a systematic review and meta-analysis

MY Liu, N Li, WA Li, H Khan - Neurological research, 2017‏ - Taylor & Francis
Aim: The etiology of hypertension is various and complex, involving both genetic and
behavioral factors. The relationship between psychosocial stress and hypertension has …

Inflammation‐driven brain and gut barrier dysfunction in stress and mood disorders

E Doney, A Cadoret, L Dion‐Albert… - European Journal of …, 2022‏ - Wiley Online Library
Regulation of emotions is generally associated exclusively with the brain. However, there is
evidence that peripheral systems are also involved in mood, stress vulnerability vs …

Inflammation in anxiety

S Salim, G Chugh, M Asghar - Advances in protein chemistry and structural …, 2012‏ - Elsevier
The idea of the existence of an interaction between the immune system and the central
nervous system (CNS) has prompted extensive research interest into the subject of “ …

Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders

SG Daniele, D Béraud, C Davenport, K Cheng… - Science …, 2015‏ - science.org
Synucleinopathies, such as Parkinson's disease and diffuse Lewy body disease, are
progressive neurodegenerative disorders characterized by selective neuronal death …

[HTML][HTML] Role of brain renin angiotensin system in neurodegeneration: an update

OA Abiodun, MS Ola - Saudi journal of biological sciences, 2020‏ - Elsevier
Renin angiotensin system (RAS) is an endocrine system widely known for its physiological
roles in electrolyte homeostasis, body fluid volume regulation and cardiovascular control in …

Lupus antibodies induce behavioral changes mediated by microglia and blocked by ACE inhibitors

J Nestor, Y Arinuma, TS Huerta, C Kowal… - Journal of Experimental …, 2018‏ - rupress.org
Neuropsychiatric lupus (NPS LE) is a frequent manifestation of systemic lupus
erythematosus (SLE). It is most often characterized by cognitive impairment, which occurs …

Neuroprotective effects of angiotensin receptor blockers

S Villapol, JM Saavedra - American journal of hypertension, 2015‏ - academic.oup.com
Angiotensin II receptor blockers (ARBs, collectively called sartans) are widely used
compounds therapeutically effective in cardiovascular disorders, renal disease, the …

Angiotensin II AT1 receptor blockers as treatments for inflammatory brain disorders

JM Saavedra - Clinical science, 2012‏ - portlandpress.com
The effects of brain AngII (angiotensin II) depend on AT1 receptor (AngII type 1 receptor)
stimulation and include regulation of cerebrovascular flow, autonomic and hormonal …

Immunology of major depression

N Müller - Neuroimmunomodulation, 2014‏ - karger.com
High levels of several proinflammatory components of the immune system, such as
interleukin-6, C-reactive protein, tumor necrosis factor (TNF)-α, or neopterin in patients …