Molecular mechanisms linking oxidative stress and diabetes mellitus

H Yaribeygi, T Sathyapalan, SL Atkin… - … medicine and cellular …, 2020 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …

Insulin resistance: Review of the underlying molecular mechanisms

H Yaribeygi, FR Farrokhi, AE Butler… - Journal of cellular …, 2019 - Wiley Online Library
Most human cells utilize glucose as the primary substrate, cellular uptake requiring insulin.
Insulin signaling is therefore critical for these tissues. However, decrease in insulin …

The role of catechins in regulating diabetes: an update review

L Wen, D Wu, X Tan, M Zhong, J **ng, W Li, D Li, F Cao - Nutrients, 2022 - mdpi.com
Catechins are key functional components in tea and have many health benefits, including
relieving diabetes. Glucose is necessary for maintaining life. However, when the glucose in …

[HTML][HTML] Statin treatment-induced development of type 2 diabetes: from clinical evidence to mechanistic insights

U Galicia-Garcia, S Jebari, A Larrea-Sebal… - International Journal of …, 2020 - mdpi.com
Statins are the gold-standard treatment for the prevention of primary and secondary
cardiovascular disease, which is the leading cause of mortality worldwide. Despite the safety …

Terminalia catappa aqueous leaf extract reverses insulin resistance, improves glucose transport and activates PI3K/AKT signalling in high fat/streptozotocin-induced …

FN Iheagwam, OT Iheagwam, MK Onuoha… - Scientific reports, 2022 - nature.com
Rising prevalence of type 2 diabetes mellitus (T2DM) in sub-Saharan Africa has
necessitated surveys of antidiabetic medicinal plants. This study assessed the antidiabetic …

Insulin resistance in mitochondrial diabetes

C Takano, E Ogawa, S Hayakawa - Biomolecules, 2023 - mdpi.com
Mitochondrial diabetes (MD) is generally classified as a genetic defect of β-cells. The main
pathophysiology is insulin secretion failure in pancreatic β-cells due to impaired …

Potential application of marine fucosyl-polysaccharides in regulating blood glucose and hyperglycemic complications

L Tang, M **ao, S Cai, H Mou, D Li - Foods, 2023 - mdpi.com
Diabetes mellitus (DM) has become the world's third major disease after tumors and
cardiovascular disease. With the exploitation of marine biological resources, the efficacy of …

Molecular mechanisms by which SGLT2 inhibitors can induce insulin sensitivity in diabetic milieu: A mechanistic review

H Yaribeygi, T Sathyapalan, M Maleki, T Jamialahmadi… - Life sciences, 2020 - Elsevier
Abstract Sodium-glucose co-transporter-2 inhibitors (SGLT2i) are a relatively newer class of
anti-hyperglycemic medications that reduce blood glucose by inhibition of renal glucose re …

Molecular mechanisms by which aerobic exercise induces insulin sensitivity

H Yaribeygi, SL Atkin… - Journal of cellular …, 2019 - Wiley Online Library
Insulin resistance is a key feature of Type 2 diabetes and an important therapeutic target to
address glycemic control to prevent diabetic complications. Lifestyle advice is the first step in …

Pathophysiology of physical inactivity‐dependent insulin resistance: a theoretical mechanistic review emphasizing clinical evidence

H Yaribeygi, M Maleki, T Sathyapalan… - Journal of diabetes …, 2021 - Wiley Online Library
The modern lifestyle has a negative impact on health. It is usually accompanied by
increased stress levels and lower physical activity, which interferes with body homeostasis …