Neuronal ensembles, defined as groups of neurons displaying recurring patterns of
coordinated activity, represent an intermediate functional level between individual neurons …

Most sensory, cognitive and motor functions depend on the interactions of many neurons. In
recent years, there has been rapid development and increasing use of technologies for …

When making a subjective choice, the brain must compute a value for each option and
compare those values to make a decision. The orbitofrontal cortex (OFC) is critically involved …

Sequential activation of neurons is a common feature of network activity during a variety of
behaviors, including working memory and decision making. Previous network models for …

The posterior parietal cortex (PPC) has an important role in many cognitive behaviours;
however, the neural circuit dynamics underlying PPC function are not well understood. Here …

Our ability to move is central to everyday life. Investigating the neural control of movement in
general, and the cortical control of volitional arm movements in particular, has been a major …

Conventional approaches to understanding consciousness are generally concerned with
the contribution of specific brain areas or groups of neurons. By contrast, it is considered …

Humans and other animals demonstrate the ability to perceive and respond to temporally
relevant information with characteristic behavioral properties. For example, the response …

We consider the problem of extracting smooth low-dimensional neural trajectories''that
summarize the activity recorded simultaneously from tens to hundreds of neurons on …

Neocortical activity is permeated with endogenously generated fluctuations, but how these
dynamics affect goal-directed behavior remains a mystery. We found that ensemble neural …