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Homeostatic synaptic plasticity: local and global mechanisms for stabilizing neuronal function
Neural circuits must maintain stable function in the face of many plastic challenges,
including changes in synapse number and strength, during learning and development …
including changes in synapse number and strength, during learning and development …
The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity
TE Chater, Y Goda - Frontiers in cellular neuroscience, 2014 - frontiersin.org
In the mammalian central nervous system, excitatory glutamatergic synapses harness
neurotransmission that is mediated by ion flow through α-amino-3-hydroxy-5-methyl-4 …
neurotransmission that is mediated by ion flow through α-amino-3-hydroxy-5-methyl-4 …
Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis
We recently described a severe, potentially lethal, but treatment-responsive encephalitis that
associates with autoantibodies to the NMDA receptor (NMDAR) and results in behavioral …
associates with autoantibodies to the NMDA receptor (NMDAR) and results in behavioral …
Synaptic plasticity: multiple forms, functions, and mechanisms
Experiences, whether they be learning in a classroom, a stressful event, or ingestion of a
psychoactive substance, impact the brain by modifying the activity and organization of …
psychoactive substance, impact the brain by modifying the activity and organization of …
The dialectic of Hebb and homeostasis
It has become widely accepted that homeostatic and Hebbian plasticity mechanisms work
hand in glove to refine neural circuit function. Nonetheless, our understanding of how these …
hand in glove to refine neural circuit function. Nonetheless, our understanding of how these …
Synaptic plasticity: taming the beast
Synaptic plasticity provides the basis for most models of learning, memory and development
in neural circuits. To generate realistic results, synapse-specific Hebbian forms of plasticity …
in neural circuits. To generate realistic results, synapse-specific Hebbian forms of plasticity …
Homeostatic plasticity in the develo** nervous system
Activity has an important role in refining synaptic connectivity during development, in part
through'Hebbian'mechanisms such as long-term potentiation and long-term depression …
through'Hebbian'mechanisms such as long-term potentiation and long-term depression …
[HTML][HTML] The self-tuning neuron: synaptic scaling of excitatory synapses
Homeostatic synaptic scaling is a form of synaptic plasticity that adjusts the strength of all of
a neuron's excitatory synapses up or down to stabilize firing. Current evidence suggests that …
a neuron's excitatory synapses up or down to stabilize firing. Current evidence suggests that …
Acute mechanisms underlying antibody effects in anti–N‐methyl‐D‐aspartate receptor encephalitis
Objective A severe but treatable form of immune‐mediated encephalitis is associated with
antibodies in serum and cerebrospinal fluid (CSF) against the GluN1 subunit of the N …
antibodies in serum and cerebrospinal fluid (CSF) against the GluN1 subunit of the N …
Similar network activity from disparate circuit parameters
It is often assumed that cellular and synaptic properties need to be regulated to specific
values to allow a neuronal network to function properly. To determine how tightly neuronal …
values to allow a neuronal network to function properly. To determine how tightly neuronal …