Transient global ischemia selectively damages neurons in specific brain areas. A
reproducible pattern of selective vulnerability is observed in the dorsal hippocampus of …

Wolfram Syndrome (WFS) is a rare, autosomal, recessive neurogenetic disorder that affects
many organ systems. It is characterised by diabetes insipidus, diabetes mellites, optic …

Anoxic depolarization of pyramidal neurons results from a large inward current that is
activated, in part, by excessive glutamate release during exposure to anoxia/ischemia …

The Wolfram syndrome is a rare autosomal recessive disease affecting many organs with
life-threatening consequences; currently, no treatment is available. The disease is caused …

The food-entrainable oscillator (FEO) is a mysterious circadian clock because its anatomical
location (s) and molecular timekee** mechanism are unknown. Food anticipatory activity …

Wolfram syndrome is a rare genetic disorder largely caused by pathogenic variants in the
WFS1 gene and manifested by diabetes mellitus, optic nerve atrophy, and progressive …

Increased fronto-temporal theta coherence and failure of its stimulus-specific modulation
have been reported in schizophrenia, but the psychological correlates and underlying …

The selection and optimization of appropriate adaptive responses depends on interoceptive
and exteroceptive stimuli as well as on the animal's ability to switch from one behavioral …

Major depressive disorder (MDD) is a prevalent illness that can be precipitated by acute or
chronic stress. Studies of patients with Wolfram syndrome and carriers have identified Wfs1 …

Mutations in WFS1 (which encodes Wolframin, WFS1) and CISD2 (which encodes CDGSH
iron sulfur domain 2) result in Wolfram syndrome (WS), a rare genetic disorder that starts …