The motor signs of Parkinson's disease are thought to result in large part from a reduction of
the level of dopamine in the basal ganglia. Over the last few years, many of the functional …

Oscillatory activities across multiple frequency bands and their cross-frequency interactions
within spatially segregated loops of the basal ganglia-thalamo-cortical system may relate to …

Abstract See Moll and Engel (doi: 10.1093/aww308) for a scientific commentary on this
article. Brain regions dynamically engage and disengage with one another to execute …

Based on recent experimental data, we have developed a conductance-based
computational network model of the subthalamic nucleus and the external segment of the …

Parkinson's disease (PD) is characterized by motor and nonmotor (cognitive and limbic)
deficits. The motor signs of PD include hypokinetic signs such as akinesia/bradykinesia …

The various forms of tremor are now classified in two axes: clinical characteristics (axis 1)
and etiology (axis 2). Electrophysiology is an extension of the clinical exam …

A substantial body of work within the last decade has demonstrated that there is a variety of
oscillatory phenomena that occur in the basal ganglia and in associated regions of the …

L-DOPA is still the most effective pharmacological therapy for the treatment of motor
symptoms in Parkinson's disease (PD) almost four decades after it was first used. Deep …

The emergence of oscillations and synchrony among neurons of the basal ganglia is a well-
known characteristic of Parkinson's disease. In this study we used intra-operative …

As the proliferation of pervasive and ubiquitous computing devices continues, users will
carry more devices. Without the ability for these devices to unobtrusively interact with one …